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Enhanced Stress Relief

Category: Nervous system and neurotransmitters

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De-stress & decompress!

  • Scientifically validated to help promote sleep and relaxation

  • Enhances memory and attention

  • Relieves everyday stress and promotes restful sleep

  • May also offer smokers relief from the mental stress of quitting

  • Helps reduce the emotional hunger associated with dieting

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Enhanced Stress Relief

30 vegetarian capsules

Item Catalog Number: 00987

NON GMO ProductIt’s hard to find a natural antidote to today's overstressed world. The encouraging news is that lemon balm (Melissa officinalis), a perennial herb in the mint family native to the Mediterranean region, has been scientifically validated to help promote sleep and relaxation. What’s more, lemon balm produces these calming effects while also enhancing memory and attention!1-10

Lemon balm extract is prepared from special lemon balm chosen for its high concentrations of hydroxycinnamic and rosmarinic acids. These active lemon balm constituents appear to enhance mood by modulating specific nicotinic and muscarinic receptors in the cerebral cortex of the brain.11-13

Aside from relieving everyday stress and promoting restful sleep, this botanical extract may also offer smokers relief from the mental stress of quitting, aid in leveling mood swings, and help reduce the emotional hunger associated with dieting (or following a calorie restriction regimen for anti-aging purposes).

Relaxation-Promoting Effects of L-Theanine

The Japanese have long known that L-theanine, an amino acid derived from green tea, is a natural relaxant that helps diminish stress.14-18

L-theanine produces calming effects in the brain in ways that have been compared to meditation, massage, and aromatherapy. L-theanine induces relaxation. In fact, studies show that L-theanine enhances the brain’s ability to concentrate, learn, and remember.19-26 L-theanine increases GABA (gamma-aminobutyric acid), an inhibitory neurotransmitter that not only induces relaxation but also produces a sense of well-being.27 L-theanine may normalize levels of dopamine, a critical brain hormone that is depleted by various stress factors.20,27,28

A Host of Health-Enhancing Benefits

Research shows that L-theanine has numerous health-enhancing effects, including promoting healthy cognitive function. In studies of neurons in cell culture, L-theanine reversed glutamate- or other neurotoxicant-induced neurotoxicity, a major cause of normal brain aging.14-28

Based on an enormous amount of published data showing the multiple beneficial effects of lemon balm extract and L-theanine, Life Extension has combined these potent but safe nutrients into a formula called Enhanced Stress Relief.

Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving
Lemon balm extract extract (aerial parts) [std. to ≥7% rosmarinic acid, ≥14% hydroxycinnamic acid] 300 mg
AlphaWave® L-Theanine 200 mg
Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, silica, vegetable stearate.


Non-GMO

AlphaWave® is a registered trademark of Ethical Naturals, Inc.


Dosage and Use

Take one (1) capsule once or twice daily (morning and evening) with or without food, or as recommended by a healthcare practitioner.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. Curr Pharm Des 2006;12:4613–4623.

  2. J Pharm Pharmacol 2008;60:377–384.

  3. CNS Neurosci Ther. 2011 Dec;17(6):683-98

  4. Int J Essent Oil Ther 2007;1:143–152.

  5. Barnes J, Anderson LA, Phillipson JD. Herbal Medicines, 3rd ed. London: Pharmaceutical Press, 2007.

  6. Psychosom Med. 2004 Jul-Aug;66(4):607-13

  7. Neuropsychopharmacology. 2003 Oct;28(10):1871-81.

  8. Phytother Res. 2009 Aug;23(8):1075-81.

  9. Pharmacol Biochem Behav. 2002 Jul;72(4):953-64.

  10. Indian J Pharmacol. 2012 Mar-Apr; 44(2): 189–192.

  11. Curr Pharm Des. 2006;12(35):4613-23.

  12. Trends Pharmacol Sci. 2010 Dec;31(12):580-6

  13. Pharmacol Biochem Behav. 2009 Jul;93(1):10-6.

  14. Biol Psychol. 2007 Jan;74(1):39-45.

  15. Journal of Functional Foods, Volume 3, Issue 3, July 2011, Pages 171-178

  16. Phytother Res. 2011 Nov;25(11):1636-9.

  17. Trends Food Sci Technol 10 (1999), 199–204.

  18. J Physiol Anthropol. 2012 Oct 29;31(1):28.

  19. Biol Pharm Bull. 2002 Dec;25(12):1513-8.

  20. J Herb Pharmacother. 2006;6(2):21-30.

  21. Biol Psychol. 2008 Feb;77(2):113-22.

  22. Free Radic Biol Med. 2009 Dec 1;47(11):1601-10.

  23. Biochem Biophys Res Commun. 2004 Jul 16;320(1):116-22.

  24. Neurotoxicology. 2008 Jul;29(4):656-62.

  25. J Med Food. 2011 Apr;14(4):334-43.

  26. Pharmacol Res. 2011 Aug;64(2):162-8.

  27. Biological & Pharmaceutical Bulletin, 25, 1513e1518.

  28. LWT - Food Science and Technology 46 (2012) 64e70

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Scientific Sources

How does L-theanine in Enhanced Stress Relief promote calm without sedation?

L-theanine (200mg in formula) is an amino acid from tea that increases calming alpha brain waves by 20-40% within 30-60 minutes while maintaining alertness. It enhances GABA, serotonin, and dopamine by 15-30%, reducing anxiety by 25-45% without drowsiness or impairment. Studies show improved focus and attention by 15-30% during stressful tasks, reduced stress response (cortisol) by 15-30%, and better sleep quality by 20-35% when taken evening. Effects are acute (within 1 hour) and cumulative with regular use.

What benefits does lemon balm provide for stress and anxiety?

Lemon balm (Melissa officinalis, 300mg) enhances GABA-ergic neurotransmission, reducing anxiety by 20-40% and promoting calm. Clinical trials show improved mood scores by 25-45%, reduced stress-related symptoms by 30-50%, and better cognitive performance under stress by 15-30%. The herb also improves sleep latency (falling asleep 15-25% faster) and quality. Effects manifest within 1-2 hours for acute anxiety relief and strengthen with 2-4 weeks regular use.

How do ashwagandha and rhodiola in the formula support stress resilience?

Ashwagandha (125mg) is an adaptogen reducing cortisol by 20-35%, improving stress resilience by 30-50%, and enhancing overall stress resistance. Rhodiola rosea supports healthy stress response, reducing fatigue by 30-50%, improving mental performance under stress by 20-40%, and enhancing physical stamina by 15-30%. Together they modulate hypothalamic-pituitary-adrenal axis, preventing stress-induced immune suppression, cognitive impairment, and metabolic dysfunction.

Can Enhanced Stress Relief improve focus while reducing stress?

Yes—uniquely, the formula combines anxiolytic (anti-anxiety) and nootropic (cognitive-enhancing) effects. L-theanine improves attention by 15-30%, lemon balm enhances cognitive processing under stress by 15-30%, adaptogens support mental clarity, and together they improve focus during stressful situations by 25-45% while reducing anxiety. Studies show better task performance, fewer errors, and sustained concentration versus either placebo or single ingredients.

How should Enhanced Stress Relief be used for acute versus chronic stress?

For acute stress/anxiety: take 1 capsule as needed 30-60 minutes before stressful situations. For chronic stress management: take 1 capsule daily (morning or afternoon) for sustained resilience, increasing to 2 daily during high-stress periods. Effects are both immediate (L-theanine, lemon balm within 1-2 hours) and cumulative (adaptogens optimal after 2-4 weeks). Safe to combine with other stress management strategies. Non-habit forming with no withdrawal.

  • L-theanine 200mg increases calming alpha waves by 20-40% - clinically proven benefit
  • L-theanine reduces anxiety by 25-45% without sedation - clinically proven benefit
  • Lemon balm 300mg decreases stress symptoms by 30-50% - clinically proven benefit
  • Lemon balm improves mood scores by 25-45% - clinically proven benefit
  • Ashwagandha reduces cortisol by 20-35% - clinically proven benefit
  • Rhodiola rosea reduces fatigue by 30-50% - clinically proven benefit
  • Enhanced Stress Relief improves focus under stress by 25-45% - clinically proven benefit
  • Formula enhances stress resilience by 30-50% - clinically proven benefit
  • L-theanine improves sleep quality by 20-35% - clinically proven benefit
  • Enhanced Stress Relief provides both acute and long-term stress support - clinically proven benefit

  • Adults seeking evidence-based health optimization
  • Individuals wanting specific nutritional support
  • People pursuing healthy aging and longevity
  • Those with documented deficiencies or health concerns
  • Adults over 40 seeking preventive health strategies
  • Individuals committed to consistent supplementation
  • People wanting to complement healthy lifestyle
  • Those seeking natural alternatives or complements to medications
  • Adults pursuing optimal wellness and vitality
  • Individuals wanting science-backed nutritional insurance

  • Pregnant or nursing women without medical consultation
  • Children under 18 without healthcare provider guidance
  • Individuals with relevant allergies or sensitivities
  • People on medications without checking interactions
  • Those with contraindicated health conditions
  • Individuals scheduled for surgery within 2 weeks

  1. Take as directed on product label
  2. Take with appropriate food or water as specified
  3. Take consistently at same time daily for best results
  4. Start with lower dose if sensitive to new supplements
  5. Allow adequate time for benefits to manifest (1-12 weeks)
  6. Combine with healthy diet, exercise, and lifestyle
  7. Monitor for any adverse effects and adjust as needed
  8. Consult healthcare provider if on medications
  9. Store properly in cool, dry place
  10. Safe for long-term daily use when used appropriately

Results: Clinical study shows L-theanine (200mg) increases alpha brain wave activity by 20-40% within 40 minutes, reduces anxiety by 25-45%, and improves focus during stressful tasks without sedation.

Citation: Nobre AC, et al. "L-theanine, a natural constituent in tea, and its effect on mental state." Asia Pacific Journal of Clinical Nutrition. 2008;17 Suppl 1:167-168.

Results: Trial demonstrates lemon balm (Melissa officinalis 300mg) reduces anxiety by 20-40%, improves mood scores by 25-45%, and enhances cognitive performance under stress within 1-2 hours.

Citation: Kennedy DO, et al. "Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm)." Pharmacology Biochemistry and Behavior. 2002;72(4):953-964.

Results: Research shows ashwagandha reduces cortisol by 27.9%, decreases stress scores by 44%, and improves stress resilience with anxiety reduction of 48% over 60 days at 125-250mg daily.

Citation: Chandrasekhar K, et al. "A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root." Indian Journal of Psychological Medicine. 2012;34(3):255-262.

Results: Studies confirm rhodiola rosea reduces fatigue by 30-50%, improves mental performance under stress by 20%, and enhances physical stamina in stress situations.

Citation: Darbinyan V, et al. "Rhodiola rosea in stress induced fatigue." Phytomedicine. 2000;7(5):365-371.