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Science-based food supplements
Manufacturer: Life Extension
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Inositol Caps 1000 mg
360 vegetarian capsules
Item Catalog Number: 01674
Inositol is a compound found in cell membranes. It encourages healthy cellular signaling, promotes healthy insulin response, and is involved in neurotransmitter modulation, which may promote mood and emotional health. Inositol also helps maintain already-healthy hormone levels.
Benefits at a Glance:
Inositol is a primary component of cell membrane phospholipids. Both membrane-bound and free inositol are important for supporting many cell functions and participate in maintaining cellular responses to external signaling. 1
For example, inositol helps support insulin responsiveness, which in turn supports healthy lipid and glucose metabolism. 2,3 Meta-analyses of clinical trials in women have shown inositol supplements can help encourage healthy insulin response and glucose metabolism, as well as support already-healthy hormone levels and reproductive system health. 4-6
Inositol-based compounds are involved in neurotransmitter activity modulation, giving inositol potential benefits in promoting mental and emotional health. Some research indicates inositol may be beneficial for supporting stable moods. 7-9
Life Extension’s Inositol Caps delivers 1,000 mg of Inositol in every capsule.
Serving Size 1 vegetarian capsule
| Amount per serving: | |
|---|---|
|
Inositol [as myo-inositol] |
1000 mg |
| Other ingredients: vegetable cellulose (capsule), vegetable stearate, silica. | |
Non-GMO
Dosage and Use
Take one (1) capsule with food, or as recommended by a healthcare practitioner.
Warnings
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Inositol is a naturally occurring compound often grouped with B-vitamins. It exists in nine forms, with myo-inositol being the most abundant. Inositol plays crucial roles in cell signaling, nerve function, fat metabolism, and mood regulation. As a component of cell membranes and precursor to important signaling molecules, it helps regulate neurotransmitters including serotonin, dopamine, and GABA.
Anxiety and panic disorders have shown response to inositol, with studies using 12-18 grams daily finding reduced panic attacks and anxiety symptoms. PCOS is another area where inositol shows promise, improving insulin sensitivity and helping restore ovulatory function. Depression, particularly when serotonin dysfunction is involved, may respond to inositol.
Doses vary based on condition. For general support, 500-2,000mg daily may be appropriate. For anxiety and mood support, research has used higher doses (12-18 grams daily). For PCOS, typical doses range from 2-4 grams daily. The 1,000mg capsule format allows flexible dosing.
Inositol has an excellent safety profile even at high doses. When adverse effects occur, they're typically mild GI symptoms, especially at higher doses or when starting supplementation. Taking divided doses throughout the day minimizes GI effects.
For anxiety, some people notice improvements within 2-4 weeks, though maximum benefits may take 4-6 weeks. For PCOS-related benefits, metabolic improvements typically emerge over 2-3 months. Mood support effects are often gradual, developing over several weeks.
Results: Double-blind study found 12 grams daily inositol reduced panic attacks and anxiety scores comparable to fluvoxamine but without side effects.
Citation: Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol. 2001;21(3):335-339.
Results: Meta-analysis showed inositol supplementation improved insulin sensitivity, restored ovulation, and improved metabolic parameters in women with PCOS.
Citation: Unfer V, Nestler JE, Kamenov ZA, Prapas N, Facchinetti F. Effects of inositol(s) in women with PCOS: a systematic review of randomized controlled trials. Int J Endocrinol. 2016;2016:1849162.
Results: Clinical trial found 18 grams daily inositol significantly reduced depression scores in patients with treatment-resistant depression.
Citation: Levine J. Controlled trials of inositol in psychiatry. Eur Neuropsychopharmacol. 1997;7(2):147-155.
Results: Safety analysis of multiple studies found inositol well-tolerated even at doses up to 18 grams daily with only mild GI effects reported.
Citation: Carlomagno G, Unfer V, Roseff S. The D-chiro-inositol paradox in the ovary. Fertil Steril. 2011;95(8):2515-2516.