1. Home
  2. Mitochondria and energy
  3. Acetyl-L-Carnitine

Acetyl-L-Carnitine

Category: Mitochondria and energy

Manufacturer:

Supports cellular energy metabolism

  • Helps maintain cellular energy metabolism

  • Helps maintain mitochondrial bioenergetics

  • Crosses the blood-brain barrier and guards against oxidative damage

  • Exerts protective effects against amyloid-beta peptide

Waiting for delivery

28,98 €

Volume discounts

Quantity Price You Save
2 27,82 € Up to 2,32 €
4 27,24 € Up to 6,96 €

By buying this product you can collect up to 28 loyalty points. Your cart will total 28 points that can be converted during next order into a voucher of 1,40 €.

Add to wishlist

More info

Acetyl-L-Carnitine

500 mg, 100 vegetarian capsules

Item Catalog Number: 01524

NON GMO ProductAn age-related effect is the reduction in the energy-producing components of the cell, resulting in reduced cellular metabolic activity, and the accumulation of cellular debris.1-7 L-carnitine helps maintain cellular energy metabolism by assisting in the transport of fatty acids from the cytosol into the mitochondria within the cell, where fats are oxidized to produce the cellular energy (adenosine triphosphate or ATP).8-13

Acetyl-L-carnitine is the acetylated ester of the amino acid L-carnitine. Acetyl-L-carnitine is an endogenous mitochondrial membrane compound that helps maintain mitochondrial bioenergetics and lowers the increased oxidative stress associated with aging.14 Acetyl-L-carnitine and L-carnitine are absorbed into the bloodstream efficiently. Both are effective at carrying long-chain fatty acids across the membrane into the mitochondria where they are burned for energy production and utilized efficiently by the cells.15-18 Acetyl-L-carnitine also crosses the blood-brain barrier and guards against oxidative damage.5,14,19-21 Amyloid-beta peptide is a principal component of plaques and is thought to be a contributor to the aging process. Acetyl-L-carnitine exerts protective effects against such neurotoxicity and oxidative stress.14

Acetyl-L-carnitine (ALC) easily crosses the blood-brain barrier and may have potential in exerting unique neuroprotective, neuromodulatory and neurotrophic properties. ALC may support youthful memory function, improve mitochondrial structure and function, inhibit age-related oxidative damage, and restore the activity of key enzymes.22-28

Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving
Vitamin C (as ascorbyl palmitate) 4 mg
Acetyl-L-Carnitine (from acetyl-L-carnitine hydrochloride) 500 mg
Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, silica.


Non-GMO


Dosage and Use

Take one (1) capsule two to four times daily, or as recommended by a healthcare practitioner.

This product is best utilized when taken on an empty stomach with water or juice in divided doses 45 minutes before breakfast and lunch.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.


  1. Physiol Rev.1998 Apr;78(2):547-81.

  2. Ann N Y Acad Sci. 2004 Jun;1019:406-11.

  3. Trends Cell Biol. 2011 Oct;21(10):569-76.

  4. Zhonghua Yi Xue Za Zhi (Taipei). 2001 May;64(5):259-70.

  5. Am J Physiol Cell Physiol. 2007 Feb;292(2):C670-86.

  6. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3064-9.

  7. Ann N Y Acad Sci. 1998 Nov 20;854:118-27.

  8. J Lipid Res. 2004 Apr;45(4):729-35.

  9. Metabolism. 1997 Dec;46(12):1454-7.

  10. Mech Ageing Dev. 1995 Oct 13;84(2):103-12.

  11. Ann N Y Acad Sci. 2002 Apr;959:491-507.

  12. Biochim Biophys Acta. 2000 Jun 26;1486(1):1-17.

  13. Am J Clin Nutr. 2007 Dec;86(6):1738-44.

  14. J Neurosci Res. 2006 Aug 1;84(2):398-408.

  15. Acta Diabetol. 2003 Oct;40 Suppl 1:S106-13.

  16. Biochim Biophys Acta. 2000 Jun 26;1486(1):1-17.

  17. Clin Pharmacokinet. 2012 Sep 1;51(9):553-72.

  18. Exp Physiol. 2008 Oct;93(10):1139-46.

  19. Neurochem Res. 2009 Apr;34(4):755-63.

  20. Ann N Y Acad Sci. 2004 Nov;1033:117-31.

  21. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1876-81. Erratum in: Proc Natl Acad Sci U S A 2002 May 14;99(10):7184.

  22. Neurochem Res. 2003 Sep;28(9):1321-8.

  23. Ann N Y Acad Sci. 2004 Nov;1033:108-16..

  24. Geriatr Gerontol Int. 2010 Jul;10 Suppl 1:S99-106

  25. Neuropharmacology. 2008 Aug;55(2):223-9.

  26. Arch Gerontol Geriatr. 2008 Mar-Apr;46(2):181-90

  27. Eur J Pharmacol. 2007 Sep 10;570(1-3):97-107.

  28. Brain Res. 2005 Nov 9;1061(2):114-7.

Customers who bought this product also bought:

17 other products in the same category:

Scientific Sources

What is Acetyl-L-Carnitine?

Acetyl-L-Carnitine (ALCAR) is acetylated form of L-carnitine that crosses blood-brain barrier more readily. Supports cellular energy production, brain health, and mitochondrial function. Acetyl group allows better brain penetration than L-carnitine.

How does ALCAR support energy?

ALCAR transports fatty acids into mitochondria for beta-oxidation and ATP production. Supports cellular energy metabolism particularly in tissues with high energy demands like brain, heart, and muscles. Essential for fatty acid metabolism.

What are cognitive benefits?

ALCAR crosses blood-brain barrier supporting brain energy metabolism and neurotransmitter synthesis. Research shows ALCAR supports cognitive function, memory, and mental clarity. Supports healthy brain aging.

How should I take Acetyl-L-Carnitine?

Take as recommended by healthcare practitioner. Can be taken with or without food. Some prefer morning dosing for energy support. Consistent daily use supports ongoing mitochondrial and cognitive benefits.

What precautions apply?

May cause mild digestive upset in some. Consult provider if pregnant, nursing, or on medications. May interact with thyroid medications or anticoagulants. Keep out of reach of children.

  • Acetylated L-carnitine - brain-accessible form
  • Crosses blood-brain barrier - cerebral benefits
  • Supports cellular energy - ATP production
  • Transports fatty acids to mitochondria - energy metabolism
  • Supports brain health - cognitive function
  • Supports memory - mental clarity
  • Supports mitochondrial function - cellular powerhouses
  • Supports neurotransmitter synthesis - acetylcholine
  • Supports healthy brain aging - neuroprotection
  • Supports heart health - cardiac energy
  • Research-backed - extensively studied

  • Individuals seeking energy support
  • Those wanting cognitive support
  • People interested in brain health
  • Individuals seeking mitochondrial support
  • Those wanting memory support
  • People over 40 - declining levels
  • Active individuals - energy demands

  • Pregnant/nursing women without guidance
  • People on thyroid medications without consultation
  • Those on anticoagulants
  • Individuals with seizure disorders
  • Children without medical supervision

  1. Follow recommended dosing
  2. With or without food
  3. Morning dosing may be preferred
  4. Consistent daily use
  5. Long-term suitable
  6. Monitor energy and cognition
  7. If on medications: consult provider
  8. Adequate hydration
  9. Storage: cool, dry place

Results: L-carnitine and acetyl-L-carnitine are essential for transporting long-chain fatty acids into mitochondria for beta-oxidation and ATP production. Critical for cellular energy metabolism particularly in high-energy tissues like heart, brain, and skeletal muscle.

Citation: Physiol Rev. 1998 Apr;78(2):547-81.

Results: Acetyl-L-carnitine crosses blood-brain barrier more readily than L-carnitine due to acetyl group. Research shows ALCAR supports brain energy metabolism, neurotransmitter synthesis (particularly acetylcholine), and neuronal membrane function.

Citation: Ann N Y Acad Sci. 2004 Jun;1019:406-11.

Results: Studies demonstrate ALCAR supports mitochondrial function and biogenesis. Supports healthy mitochondrial membrane potential and ATP synthesis. Mitochondrial function declines with aging; ALCAR supplementation supports mitochondrial health.

Citation: Trends Cell Biol. 2011 Oct;21(10):569-76.

Results: Research shows ALCAR supports cognitive function including memory, attention, and mental clarity. Effects attributed to enhanced brain energy metabolism, acetylcholine synthesis, and neuroprotective properties. Particularly beneficial for age-related cognitive changes.