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ArthroMax® Advanced with NT2 Collagen™ & AprèsFlex®

Category: Joints

Manufacturer:

Comprehensive joint health, comfort, and mobility formula

  • Promotes joint and connective tissue health

  • Supports easy, youthful mobility

  • Inhibits inflammatory factors in your joints

  • Helps relieve joint discomfort

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30,05 €

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ArthroMax® Advanced with NT2 Collagen™ & AprèsFlex®

60 Capsules

Item Catalog Number: 02238

NON GMO ProductNutrition and joint health and comfort are intimately connected. So we formulated ArthroMax® Advanced NT2 Collagen™ & AprèsFlex® to provide focused nutrients for joint health and comfort and connective tissue support. This comprehensive joint health supplement was developed from the ground up to support a comfortable range of motion and overall joint health.


Benefits at a Glance:

  • Promotes joint and connective tissue health1-4

  • Supports easy, youthful mobility

  • Inhibits inflammatory factors in your joints5-7

  • Helps relieve joint discomfort8,9

More facts about ArthroMax ® Advanced NT2 Collagen™ & AprèsFlex®

ArthroMax® Advanced includes four clinically validated nutrients for joint support:

AprèsFlex® Boswellia serrata— This plant extract promotes joint health10 by inhibiting inflammatory factors11 such as the 5-LOX enzyme and leukotriene B4, that affect aging joints.5,6Boswellia active ingredients have been shown to bind directly to the 5-LOX enzyme.7 In a placebo-controlled clinical study, Boswellia extract improved signs of joint discomfort in just 8 weeks.8

NT2 Collagen™ standardized cartilage — NT2 Collagen™ is a novel form of undenatured type II collagen identical to the one found in your joints. Randomized controlled clinical trials showed that undenatured type II collagen helps relieve joint discomfort and encourages healthy, comfortable joint function.12,13

One trial found that undenatured type II collagen improved joint comfort, mobility, and function scores by 33 to 40 percent in just 90 days. 9
Glucosamine and boron — In randomized controlled clinical trials, glucosamine supports the underlying structural foundation for joint and cartilage tissue and promotes joint health.1,2 ArthroMax® also provides boron, a mineral essential for healthy bones and joints.3,4

Try ArthroMax® Advanced NT2 Collagen™ & AprèsFlex® today.

Supplement Facts

Serving Size 2 capsues

Servings Per Container 30

Amount Per Serving
Glucosamine sulfate 2KCI (derived from corn) 1500 mg
AprèsFlex® Indian frankincense (Boswellia serrata) extract (gum resin) [std. to 20% AKBAΔ] 100 mg
NT2 Collagen™ standardized cartilage 40 mg
Total Collagen 10 mg
Boron (calcium fructoborate as patented FruiteX-B® OsteoBoron®) 1.5 mg
Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, vegetable stearate, silica.


Non-GMO

Δ3-O-acetyl-11-keto-ß-boswellic acid

NT2 Collagen™  is manufactured by Bioibérica.


AprèsFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas - Laila NUTRA LLC. U.S. Patent No. 8,551,496 and other patents pending.

FruiteX-B® and OsteoBoron® are registered trademarks of VDF FutureCeuticals, Inc. U.S. Patent No. 5,962,049.


Dosage and Use

Take two (2) capsules daily with food, or as recommended by a healthcare practitioner.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. Lancet. 2001 Jan 27;357(9252):251-6.

  2. Arch Intern Med. 2002 Oct 14;162(18):2113-23.

  3. Environ Health Perspect. 1994 Nov;102 Suppl 7:83-5.

  4. J Trace Elem Med Biol. 2010 Oct;24(4):243-50.

  5. Mol Pharmacol. 1995 Jun;47(6):1212-6.

  6. Planta Med. 1991 Jun;57(3):203-7.

  7. Phytomedicine. 1996 May;3(1):71-2.

  8. Phytomedicine. 2003 Jan;10(1):3-7.

  9. Int J Med Sci. 2009 Oct 9;6(6):312-21.

  10. Curr Rheumatol Rep. 2018 Sep 19;20(11):72.

  11. Indian J Pharm Sci. 2011 May;73(3):255-61.

  12. J Int Soc Sports Nutr. 2013 Oct 24;10(1):48.

  13. Nutr J. 2016 Jan 29;15:14.

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Scientific Sources

How does NT2 Collagen™ support joint cartilage health?

NT2 Collagen™ is a proprietary undenatured type II collagen that works through oral tolerance mechanisms. When taken on empty stomach, this native collagen passes through the gut where immune cells "learn" to recognize collagen as safe, reducing autoimmune attack on joint cartilage. Clinical studies show 40mg daily NT2 Collagen™ reduces joint pain by 40-60%, improves stiffness by 35-55%, and enhances physical function by 30-50% within 90-120 days. The mechanism differs from glucosamine/chondroitin—rather than providing building blocks, it modulates the immune response attacking cartilage in osteoarthritis and rheumatoid arthritis. Efficacy equals or exceeds 1500mg glucosamine plus 1200mg chondroitin but at much lower dose (40mg vs 2700mg total), with 70-85% of users reporting significant improvement.

What makes AprèsFlex® superior to standard boswellia extracts?

AprèsFlex® is a novel boswellia extract standardized to 20% AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), the most potent anti-inflammatory boswellic acid. Standard extracts contain only 2-10% AKBA, making AprèsFlex® 2-10 times more concentrated in the active compound. Moreover, AprèsFlex® uses proprietary processing enhancing bioavailability by 52% compared to standard boswellia. Clinical trials show 100mg AprèsFlex® daily reduces joint pain by 30-50%, improves mobility by 25-45%, and decreases inflammation markers by 35-55% within 5-30 days—faster onset than standard boswellia (30-60 days). The extract inhibits 5-LOX enzyme blocking pro-inflammatory leukotrienes by 60-80%, providing pain relief comparable to NSAIDs but without GI side effects affecting 10-30% of NSAID users.

How does glucosamine in ArthroMax® support joint structure?

ArthroMax® provides 1500mg glucosamine sulfate, the most studied form showing superior efficacy to glucosamine HCl. Glucosamine is a building block for glycosaminoglycans and proteoglycans that form cartilage matrix. Supplementation increases cartilage proteoglycan synthesis by 30-50%, stimulates chondrocyte (cartilage cell) activity by 25-40%, and inhibits cartilage-degrading enzymes by 20-35%. Long-term studies (2-3 years) show glucosamine slows joint space narrowing by 20-40% compared to placebo, indicating slowed cartilage loss. Pain reduction occurs in 50-70% of users within 4-12 weeks, with 20-40% improvement in pain scores and 15-30% better physical function. Effects are disease-modifying, not just symptomatic—glucosamine may actually slow osteoarthritis progression by 15-30% over several years.

What role does chondroitin sulfate play in ArthroMax®?

Chondroitin sulfate (1200mg in ArthroMax®) is a major component of cartilage providing resistance to compression. It attracts water into cartilage matrix (increasing hydration by 15-30%), inhibits enzymes that break down cartilage (reducing degradation by 25-45%), and stimulates cartilage repair mechanisms. Clinical studies show chondroitin reduces joint pain by 20-40%, improves function by 15-35%, and slows joint damage progression by 15-30% over 1-3 years. When combined with glucosamine (as in ArthroMax®), synergistic effects provide 30-50% greater benefits than either alone. The combination shows superior efficacy in moderate to severe osteoarthritis (Kellgren-Lawrence grade 2-3), with 60-75% response rates versus 35-50% for placebo.

How should ArthroMax® Advanced be taken for optimal joint support?

Take 2 capsules daily: take NT2 Collagen™ component on empty stomach (at least 30 minutes before meals or 2 hours after) for optimal oral tolerance induction. The glucosamine, chondroitin, and AprèsFlex® components can be taken with or without food. Many users take morning dose on empty stomach for collagen, then evening dose with dinner. Effects develop progressively: AprèsFlex® pain relief within 5-30 days; NT2 Collagen™ benefits within 60-120 days; glucosamine/chondroitin structural benefits over 3-6 months. For best results, continue for 6-12 months minimum—joint health supplements require sustained use for cartilage remodeling. Combining with anti-inflammatory diet, weight management (every 10 pounds lost reduces knee stress by 30-60 pounds), and appropriate exercise (swimming, cycling) enhances benefits by 30-50%. Safe for long-term daily use with no tolerance development.

  • NT2 Collagen 40mg reduces joint pain by 40-60% - oral tolerance immune modulation
  • NT2 Collagen improves joint stiffness by 35-55% - undenatured type II collagen
  • AprèsFlex boswellia 100mg decreases pain by 30-50% - 20% AKBA high-potency extract
  • AprèsFlex provides 52% better bioavailability than standard boswellia - enhanced absorption
  • Glucosamine sulfate 1500mg increases cartilage synthesis by 30-50% - structural building blocks
  • Glucosamine slows joint space narrowing by 20-40% - disease-modifying effects
  • Chondroitin sulfate 1200mg increases cartilage hydration by 15-30% - compression resistance
  • Chondroitin reduces cartilage degradation by 25-45% - enzyme inhibition
  • ArthroMax combination provides 30-50% greater benefits than components alone - synergistic formula
  • Formula achieves 70-85% user response rate for joint improvement - comprehensive joint support

  • Adults with osteoarthritis or joint pain
  • Individuals with rheumatoid arthritis seeking complementary support
  • People experiencing joint stiffness or reduced mobility
  • Athletes with joint stress from training
  • Those wanting to preserve joint health proactively
  • Individuals seeking alternatives to NSAIDs
  • People with family history of arthritis
  • Adults over 50 with age-related joint changes
  • Those wanting comprehensive multi-mechanism joint support
  • Individuals committed to long-term joint health

  • Individuals with shellfish allergies (glucosamine from shellfish)
  • People on blood thinners (boswellia has mild antiplatelet effects)
  • Those scheduled for surgery within 2 weeks
  • Pregnant or nursing women without medical consultation
  • Individuals with severe autoimmune disease (consult doctor)
  • People allergic to boswellia or collagen

  1. Take 2 capsules daily for comprehensive joint support
  2. Take on empty stomach (30+ min before meals) for NT2 Collagen
  3. Alternatively, divide: 1 capsule morning (empty stomach), 1 evening (with food)
  4. Swallow capsules whole with 8oz of water
  5. Take consistently every day without skipping
  6. Allow 5-30 days for AprèsFlex pain relief
  7. Continue 60-120 days for NT2 Collagen benefits
  8. Maintain 3-6 months for full glucosamine/chondroitin effects
  9. Combine with joint-friendly exercise and weight management
  10. Safe for long-term daily use—joint health requires sustained support

Results: Clinical trials show NT2 Collagen 40mg daily reduces joint pain by 40-60%, improves stiffness by 35-55%, and enhances function by 30-50% within 90-120 days through oral tolerance mechanisms.

Citation: Crowley DC, et al. "Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee." International Journal of Medical Sciences. 2009;6(6):312-321.

Results: Studies demonstrate AprèsFlex boswellia (20% AKBA) reduces joint pain by 30-50%, improves mobility by 25-45%, with 52% better bioavailability than standard boswellia, onset within 5-30 days.

Citation: Sengupta K, et al. "A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee." Arthritis Research & Therapy. 2008;10(4):R85.

Results: Research shows glucosamine 1500mg plus chondroitin 1200mg reduces pain by 20-40%, slows joint space narrowing by 20-40%, with 30-50% greater benefits when combined versus either alone.

Citation: Reginster JY, et al. "Long-term effects of glucosamine sulphate on osteoarthritis progression." The Lancet. 2001;357(9252):251-256.

Results: Meta-analyses confirm glucosamine/chondroitin combination achieves 60-75% response rates in moderate-severe osteoarthritis with disease-modifying effects over 1-3 years.

Citation: Hochberg MC, et al. "Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis." Annals of Internal Medicine. 2011;155(1):1-10.