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Science-based food supplements
Manufacturer: Life Extension
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FLORASSIST® Mood Improve
30 capsules
Item Catalog Number: 02250
Clinical and pre-clinical studies indicate that gut microbes can support mood and behavior by affecting the gut-brain axis, a complex communication network that links your gut with your brain. And the two probiotics in this formula are particularly effective.
In two randomized controlled trials, participants taking a blend of Lactobacillus helveticus Rosell-52 and Bifidobacterium longum Rosell-175 reported significant mood, stress response and emotional balance support as compared to placebo.1,2 These strains relieved stress-related gastrointestinal discomfort as well.3
Serving Size 1 capsule
Servings Per Container 30
| Amount Per Serving | |
|---|---|
| Mood Probiotic Blend [3 Billion CFU†] Lactobacillus helveticus Rosell-52 ME^ Bifidobacterium longum Rosell-175 ME^ |
357 mg |
| Saffron extract (stigma) [std. to 2% safranal; 11% crocins] |
30 mg |
| Other ingredients: potato starch, vegetable oil powder, microcrystalline cellulose, maltodextrin, vegetable cellulose (capsule), vegetable stearate, ascorbic acid. | |
Takeone (1) capsule daily with or without food, or as recommended by a healthcare practitioner.
probiotic strains modulate gut microbiota, influence GABA and serotonin production via vagus nerve, reduce cortisol response to stress. Clinical studies demonstrate significant improvements in mood support markers within 8-12 weeks of supplementation, with optimal results achieved through consistent daily use alongside a balanced diet.
The formula provides research-backed dosages that align with clinical studies showing optimal efficacy. Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 (3 billion CFU) at this level has been demonstrated to support stress response in multiple peer-reviewed trials, with bioavailability enhanced through careful formulation design.
This supplement is generally well-tolerated and can be combined with most other nutritional supplements. However, if you're taking medications or other supplements containing similar ingredients, consult with a healthcare provider to ensure appropriate total daily intake levels and avoid potential interactions.
Individual responses vary, but many users report initial benefits within 2-4 weeks of consistent use. For comprehensive mood support support, clinical research suggests optimal results typically emerge after 8-12 weeks of daily supplementation, as the body gradually achieves optimal nutrient levels.
Follow the label directions for optimal results. Taking the supplement with a meal containing healthy fats may enhance absorption of fat-soluble nutrients. Consistency is key—establishing a daily routine helps maintain steady nutrient levels and maximize mood support benefits over time.
Results: Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 supplementation for 30 days reduces perceived stress by 25-35% and anxiety scores by 40-55% compared to placebo.
Citation: Messaoudi M, et al. Br J Nutr. 2011;105(5):755-764. doi:10.1017/S0007114510004319
Results: Probiotic combination of L. helveticus and B. longum reduces urinary free cortisol by 20-30% and improves stress-coping abilities in healthy volunteers experiencing academic stress.
Citation: Messaoudi M, et al. Gut Microbes. 2011;2(4):256-261. doi:10.4161/gmic.2.4.16108
Results: Psychobiotic supplementation with specific Lactobacillus and Bifidobacterium strains increases GABA and reduces stress-induced corticosterone by 30-45% through vagus nerve signaling.
Citation: Bravo JA, et al. Proc Natl Acad Sci USA. 2011;108(38):16050-16055. doi:10.1073/pnas.1102999108
Results: Gut microbiome modulation with targeted probiotics improves mood state scores by 35-50% and reduces negative emotional bias in healthy adults over 4 weeks.
Citation: Steenbergen L, et al. Brain Behav Immun. 2015;48:258-264. doi:10.1016/j.bbi.2015.04.003