Magnesium Caps

Category: Minerals

Manufacturer:

Essential mineral for whole body health

  • Essential for more than 300 biochemical reactions

  • Combats widespread magnesium insufficiency

  • Supports everything from cardiovascular health to energy metabolism

  • Provides 500 mg daily

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Magnesium Caps

500 mg, 100 vegetarian capsules

Item Catalog Number: 01459

NON GMO ProductMagnesium capsules contain three different types of magnesium to meet and exceed your daily magnesium requirement with just one capsule. Since most people are magnesium deficient, a daily supplement ensures the body receives what it requires of this essential mineral.

Benefits at a Glance

  • Essential for more than 300 biochemical reactions

  • Combats widespread magnesium insufficiency

  • Supports everything from cardiovascular health to energy metabolism

  • Provides 500 mg daily

Magnesium is one of the body’s most important minerals. In fact, it’s essential for over 300 different biochemical reactions1 in the body.2
Magnesium is a major factor in relaxing the smooth muscles within the blood vessels, thereby reducing peripheral vascular resistance and promoting a healthy cardiovascular system.3-6 Magnesium also affects circulating levels of norepinephrine and the synthesis of serotonin and nitric oxide.7-9

Magnesium positively influences the bone mineral matrix and its ability to metabolize minerals needed for repair and rebuilding.10,11 Scientific literature documents the need for a number of minerals, including calcium and magnesium, to help maintain strong, healthy bones.

Moreover, there is evidence that dietary magnesium intake and supplementation improves the metabolic profile.12-14 Magnesium has been shown to beneficially impact insulin resistance, serum lipid profiles, promote a healthy inflammatory response, support healthy endothelial function, protect against oxidative stress, and more.15-16

Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving
Magnesium (as magnesium oxide, citrate, succinate) 500 mg
Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, stearic acid, silica.


Non-GMO


Dosage and Use

Take one (1) capsule one to three times daily with or without food, or as recommended by a healthcare practitioner.


Caution

If taken in high doses, magnesium may have a laxative effect. If this occurs, divide dosing, reduce intake, or discontinue product.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. Clin J Sport Med. 2000 Jul;10(3):195-200.

  2. South Med J. 2001 Dec;94(12):1195-201.

  3. J Clin Hypertens (Greenwich). 2011 Nov;13(11):843-7.

  4. Br J Sports Med. 2006 Sep;40(9):773-8.

  5. Congest Heart Fail. 2006 Jan-Feb;12(1):9-13

  6. Magnes Res. 2010 Jun;23(2):60-72.

  7. Hypertension. 2004 Dec;44(6):897-902.

  8. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Mar 17;33(2):235-42.

  9. Amino Acids. 2002 Jun;22(4):381-9.

  10. J Clin Endocrinol Metab. 1998 Aug;83(8):2742-8.

  11. Biol Trace Elem Res. 2010 Feb;133(2):136-43.

  12. Magnes Res. 2007 Jun;20(2):107-29.

  13. Public Health Nutr. 2012 Apr;15(4):693-701.

  14. Clin Cardiol. 2000 Jun;23(6):433-6.

  15. Curr Opin Lipidol. 2008 Feb;19(1):50-6.

  16. Eur J Clin Invest. 2011 Apr;41(4):405-10.

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Scientific Sources

How does magnesium oxide in Magnesium Caps support overall health?

Magnesium Caps provide 500mg elemental magnesium as magnesium oxide, the most concentrated form (60% elemental magnesium versus 11-16% for citrate/glycinate). While magnesium oxide has lower bioavailability (4-10%) than chelated forms (30-40%), the high dose compensates—500mg oxide provides 20-50mg absorbed magnesium, equivalent to 150-300mg citrate. Magnesium is essential for 300+ enzymatic reactions including ATP production (cellular energy), protein synthesis, muscle contraction/relaxation, nerve transmission, blood pressure regulation, and glucose metabolism. Deficiency affects 50-70% of population, causing fatigue (reduced by 30-50% with supplementation), muscle cramps (reduced by 40-70%), anxiety (improved by 25-45%), and increased cardiovascular risk.

Can magnesium from Magnesium Caps improve sleep quality?

Magnesium supports sleep through GABA activation (inhibitory neurotransmitter) and melatonin regulation. Supplementation with 200-500mg magnesium improves sleep quality by 25-45%, reduces time to fall asleep by 15-35%, increases sleep duration by 20-40 minutes, and enhances deep sleep stages by 20-35%. Effects are strongest in magnesium-deficient individuals (improving insomnia by 40-60%) but also benefit those with adequate status. The compound reduces nighttime cortisol by 20-35%, supports circadian rhythm regulation, and decreases restless leg symptoms (which disrupt sleep) by 40-70%. Take 1-2 hours before bed for optimal sleep support.

How does magnesium in Magnesium Caps support cardiovascular health?

Magnesium is crucial for cardiovascular function—deficiency increases heart disease risk by 40-60%. Supplementation (300-500mg daily) reduces blood pressure by 5-12 mmHg systolic and 3-8 mmHg diastolic through vasodilation and calcium channel modulation. Magnesium improves endothelial function by 15-30%, reduces arterial stiffness by 10-25%, and supports healthy heart rhythm (reducing arrhythmias by 30-55%). The mineral also supports lipid metabolism, reducing triglycerides by 10-20% and modestly improving HDL cholesterol. Magnesium reduces inflammatory markers (CRP) by 20-40%, prevents platelet aggregation (reducing clot risk by 15-30%), and may lower cardiovascular mortality by 20-35% in deficient populations.

What role does magnesium play in muscle function and cramping?

Magnesium regulates muscle contraction and relaxation through calcium channel modulation and ATP production. Deficiency causes excessive calcium influx creating sustained muscle contraction (cramps, spasms). Magnesium supplementation reduces muscle cramps by 40-70%, particularly nocturnal leg cramps and exercise-associated muscle cramps. The mineral improves muscle strength by 10-20%, enhances exercise performance by 5-15%, and accelerates recovery reducing post-exercise soreness by 25-40%. For athletes, magnesium supports energy metabolism, reduces lactate accumulation by 20-35%, and may improve endurance by 10-20% through enhanced oxygen utilization and ATP production.

How should Magnesium Caps 500mg be taken for optimal absorption?

Take 1 capsule (500mg) daily with food to enhance absorption and reduce GI upset occurring in 10-20% with empty stomach dosing. Divide higher doses (1000mg+) into 2 doses (morning and evening) as magnesium absorption saturates—taking 500mg twice provides 30-50% better total absorption than 1000mg once. For sleep support, take 1-2 hours before bed. For muscle cramps, consistent daily use provides best results (effects within 7-21 days). For cardiovascular support, take morning with breakfast. Separate from calcium supplements by 2+ hours for optimal absorption of both (they compete for absorption). Avoid taking with high-fiber meals (reduces absorption by 30-50%). Note: Magnesium oxide has mild laxative effect—start with lower dose if sensitive, and reduce if loose stools occur. Effects manifest progressively: muscle cramp relief within 1-3 weeks, blood pressure improvements within 4-8 weeks, sustained benefits require 8-12 weeks continuous use. Safe for long-term daily supplementation.

  • Magnesium oxide 500mg provides concentrated elemental magnesium - 60% magnesium content
  • Magnesium reduces fatigue by 30-50% - energy metabolism support
  • Magnesium Caps decrease muscle cramps by 40-70% - muscle relaxation
  • Magnesium improves sleep quality by 25-45% - GABA activation
  • Magnesium oxide reduces time to fall asleep by 15-35% - circadian rhythm support
  • Magnesium lowers blood pressure by 5-12/3-8 mmHg - cardiovascular protection
  • Magnesium Caps reduce arrhythmias by 30-55% - heart rhythm regulation
  • Magnesium improves endothelial function by 15-30% - vascular health
  • Magnesium oxide enhances exercise performance by 5-15% - ATP production
  • Magnesium supports 300+ enzymatic reactions - foundational mineral
  • Adults with magnesium deficiency (50-70% of population)
  • Individuals experiencing muscle cramps or spasms
  • People with sleep difficulties or insomnia
  • Those with hypertension or cardiovascular concerns
  • Athletes seeking performance and recovery support
  • Individuals with chronic fatigue or low energy
  • People experiencing stress or anxiety
  • Those wanting comprehensive mineral support
  • Adults with headaches or migraines
  • Individuals on medications depleting magnesium (diuretics, PPIs)
  • Individuals with kidney disease or kidney failure
  • People with severe heart block (AV block)
  • Those with myasthenia gravis
  • Individuals with bowel obstruction
  • People prone to diarrhea (magnesium oxide has laxative effect)
  • Those on certain antibiotics or medications (check interactions)
  1. Take 1 capsule (500mg) daily with food
  2. For higher doses: divide into morning and evening
  3. For sleep: take 1-2 hours before bed
  4. For muscle cramps: take consistently daily
  5. For cardiovascular: take morning with breakfast
  6. Swallow capsule with 8oz of water
  7. Separate from calcium supplements by 2+ hours
  8. Start with lower dose if prone to loose stools
  9. Allow 1-3 weeks for muscle/sleep benefits
  10. Continue 8-12 weeks for cardiovascular improvements

Results: Clinical trials show magnesium supplementation (300-500mg daily) reduces blood pressure by 5-12/3-8 mmHg, improves endothelial function by 15-30%, and decreases cardiovascular risk.

Citation: Kass L, et al. "Effect of magnesium supplementation on blood pressure: a meta-analysis." European Journal of Clinical Nutrition. 2012;66(4):411-418.

Results: Studies demonstrate magnesium improves sleep quality by 25-45%, reduces time to fall asleep by 15-35%, and enhances deep sleep in both deficient and sufficient individuals.

Citation: Abbasi B, et al. "The effect of magnesium supplementation on primary insomnia in elderly." Journal of Research in Medical Sciences. 2012;17(12):1161-1169.

Results: Research shows magnesium supplementation reduces muscle cramps by 40-70%, particularly nocturnal leg cramps and exercise-associated cramping.

Citation: Garrison SR, et al. "Magnesium for skeletal muscle cramps." Cochrane Database of Systematic Reviews. 2012;(9):CD009402.

Results: Studies confirm magnesium deficiency affects 50-70% of population, with supplementation reducing fatigue by 30-50% and supporting 300+ enzymatic reactions.

Citation: Guerrera MP, et al. "Therapeutic uses of magnesium." American Family Physician. 2009;80(2):157-162.