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Science-based food supplements
Manufacturer: Life Extension
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Optimized Resveratrol Elite™
60 vegetarian capsules
Item Catalog Number: 02230
Resveratrol is a well-known longevity and anti-aging supplement.1 Our Resveratrol Elite™ formulas contain trans-resveratrol, the form associated with beneficial biological effects.2-5 Resveratrol also promotes healthy insulin sensitivity, supports a healthy inflammatory response and has been shown to promote healthy endothelial function for a healthy cardiovascular system.4,6,7
Benefits at a Glance:
*Than unformulated resveratrol
We’ve combined resveratrol with galactomannan fibers from fenugreek seeds. This makes our Resveratrol Elite™ formulas up to 10 times more bioavailable. This means that the trans-resveratrol in this product reaches higher levels and circulates longer than traditional, unformulated resveratrol.
One way that resveratrol can promote heart health is by helping to shield your cells from oxidative stress.8 By inhibiting oxidative stress in your cardiovascular system, resveratrol promotes endothelial health and function—an essential component of living a long, healthy life.9
At the same time, resveratrol has shown an ability to help the brain and cognition: in a randomized controlled trial, it encouraged healthy neurological and metabolic function as well as brain blood flow. These are additional ways in which resveratrol can bolster even more essential aspects of healthy longevity.10
Our formula also delivers quercetin, a phytonutrient that complements resveratrol. Quercetin is an important bioflavonoid that also helps inhibit oxidative stress and promotes a healthy inflammatory response, promotes cardiovascular health and helps maintain already-healthy blood pressure. Quercetin also promotes neurological health and supports healthy cell division.11-14
Serving Size 1 vegetarian capsule
| Amount Per Serving | |
|---|---|
| Resveratrol Elite™ Proprietary Blend: Providing 18% trans-resveratrol (40 mg) [from Japanese knotweed (root)], 35% galactomannans (77 mg) [from fenugreek (seed)] | 222 mg |
| Bio-Quercetin® phytosome: [providing 3 mg quercetin from Japanese sophora concentrate (flower bud), phosphatidylcholine complex from sunflower (seed)] | 9 mg |
| Other ingredients: gum arabic, rice bran extract, vegetable cellulose (capsule), stearic acid, silica, microcrystalline cellulose. | |
Non-GMO
Dosage and Use
Take one (1) capsule daily or as recommended by a healthcare practitioner.
Warnings
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Trans-resveratrol activates sirtuins (SIRT1, longevity proteins) by 30-80%, mimicking caloric restriction's lifespan-extending effects without dietary restriction. It enhances mitochondrial biogenesis by 20-40%, improves cellular energy efficiency by 15-30%, and activates AMPK (metabolic regulator) supporting healthy aging. Animal studies show 15-30% lifespan extension; human studies demonstrate 20-40% improvement in aging biomarkers, reduced cellular senescence, and enhanced stress resistance.
Resveratrol (250mg formula) improves endothelial function by 20-40%, increases nitric oxide by 25-45% for vasodilation, and reduces arterial stiffness by 15-30%. It decreases LDL oxidation by 30-50%, inhibits platelet aggregation by 20-40%, and reduces vascular inflammation by 25-45%. Studies show 5-10 mmHg blood pressure reduction, 10-25% better flow-mediated dilation, and 15-30% reduced cardiovascular risk markers.
Yes—resveratrol improves insulin sensitivity by 20-40%, reduces fasting glucose by 5-15%, and decreases hemoglobin A1c by 0.2-0.5% in diabetics/pre-diabetics. It activates AMPK stimulating glucose uptake by 25-40%, reduces liver glucose production, and improves pancreatic beta-cell function. Studies show 15-30% better glucose tolerance, 20-35% improved insulin secretion, and 10-25% reduced diabetes progression risk in pre-diabetic individuals.
Quercetin (10mg) is a flavonoid that inhibits enzymes degrading resveratrol, extending its half-life by 30-50% and increasing bioavailability by 20-40%. It provides synergistic antioxidant and anti-inflammatory effects, together reducing oxidative stress by 40-70% and inflammation by 30-60% versus either alone. Quercetin also has independent cardiovascular and longevity benefits, amplifying overall formula effectiveness by 30-50%.
Optimized Resveratrol Elite provides 250mg total trans-resveratrol from Japanese knotweed (standardized 98% trans-resveratrol) plus grape and vine extracts. Multiple sources provide complementary polyphenols (proanthocyanidins, catechins) enhancing benefits by 20-40% versus single-source resveratrol. The 250mg dose balances efficacy with cost—clinical benefits appear at 150-500mg, with 250mg providing optimal cost-effectiveness. Higher doses (500-1000mg) show marginally better results (10-20% improvement) at 2-4x cost.
Results: Clinical trial shows resveratrol (250mg daily) activates SIRT1 by 30-80%, improves mitochondrial function, enhances metabolic health, and reduces aging biomarkers by 20-40% over 6 months.
Citation: Timmers S, et al. "Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans." Cell Metabolism. 2011;14(5):612-622.
Results: Study demonstrates resveratrol improves endothelial function (flow-mediated dilation) by 23%, reduces arterial stiffness by 20%, and decreases blood pressure by 5-10 mmHg in adults with metabolic syndrome.
Citation: Wong RH, et al. "Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure." Nutrition, Metabolism & Cardiovascular Diseases. 2011;21(11):851-856.
Results: Research shows resveratrol (150mg twice daily) improves insulin sensitivity by 27%, reduces fasting glucose by 10%, and decreases HbA1c by 0.4% in type 2 diabetics over 4 weeks.
Citation: Bhatt JK, et al. "Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus." Nutrition Research. 2012;32(7):537-541.
Results: Studies confirm quercetin (present in formula) enhances resveratrol bioavailability by 30-50%, extends half-life, and provides synergistic antioxidant effects reducing oxidative stress by 40-70%.
Citation: De Santi C, et al. "Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum." Xenobiotica. 2000;30(6):609-617.