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Science-based food supplements
Manufacturer: Life Extension
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Melatonin 6 Hour Timed Release
750 mcg , 60 vegetarian tablets
Item Catalog Number: 01788
Melatonin increases the speed of falling asleep and promotes sleep quality.1 It also has strong antioxidant properties and is important for protecting cellular DNA.2,3 And our Melatonin 6 Hour formula releases 750 mcg of melatonin gradually to help you stay asleep.
Melatonin is a hormone derived from the amino acid tryptophan. Melatonin is primarily synthesized by your pineal gland and released mostly at night.
In addition to healthy sleep support, melatonin has been shown to support immune health, healthy brain function and more.4-7
A good night's sleep is crucial for overall health and well-being. But many people experience difficulty falling asleep and staying asleep. Healthy sleep patterns are governed by your body's circadian rhythm and proper melatonin secretion is essential to maintaining a healthy circadian rhythm.1
But melatonin release declines with age and can be affected by jet lag, shift work and more. Melatonin promotes healthy sleep/wake patterns and encourages onset and quality of sleep, and fosters morning alertness and overall quality of life.1,8,9
Melatonin is especially important for healthy cellular DNA and mitochondria support because it helps inhibit oxidative damage. Melatonin does this more effectively than many other antioxidants.2,3,10
Melatonin has a beneficial impact on the immune system. It can activate immune response when more is necessary, but also help restrain overactive immune response. This combined effect is known as modulation, making melatonin a true immune supporter.4
Melatonin has shown a strong relationship with promoting cognitive health.11 Melatonin supplementation has been shown in clinical trials to help support healthy cognitive function.5,6,12
Serving Size 1 vegetarian tablet
| Amount Per Serving | |
|---|---|
| Melatonin | 750 mcg |
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Other ingredients: microcrystalline cellulose, hydroxypropyl methylcellulose, hydroxypropylcellulose, aqueous film coating (purified water, hydroxypropyl methylcellulose, glycerin), stearic acid, vegetable stearate, croscarmellose sodium, silica. |
|
Non-GMO
Take one (1) tablet 30 to 60 minutes before bedtime, or as recommended by a healthcare practitioner.
Melatonin is naturally secreted from the pineal gland at night, and should be taken at night for optimal results.
Caution
Do not consume alcohol, drive or operate machinery after taking this product.
Melatonin 750mcg in timed-release formula provides sustained 6-hour delivery. Supports healthy sleep onset and sleep maintenance throughout night. Clinical research demonstrates measurable benefits.
Timed-release prevents middle-of-night awakening from melatonin drop. Supports healthy circadian rhythm regulation and sleep-wake cycles. Research-backed dosages for optimal results.
Generally well-tolerated. Consult healthcare provider if taking medications.
Many users report benefits within 2-4 weeks. Optimal results after 8-12 weeks.
Follow label directions. Take with food for best absorption. Maintain consistency.
Results: Melatonin supplementation at 0.5-5mg reduces sleep onset latency by 7-12 minutes, increases total sleep time by 13-15 minutes, and improves sleep quality scores.
Citation: Ferracioli-Oda E, et al. PLoS One. 2013;8(5):e63773. doi:10.1371/journal.pone.0063773
Results: Timed-release melatonin formulations provide sustained blood levels for 6-8 hours, reducing nighttime awakenings by 40-60% compared to immediate-release forms.
Citation: Luthringer R, et al. Hum Psychopharmacol. 2009;24(3):239-249. doi:10.1002/hup.1013
Results: Melatonin supports circadian rhythm regulation, improves sleep quality in shift workers by 30-50%, and reduces jet lag symptoms by 50% when used appropriately.
Citation: Herxheimer A, Petrie KJ. Cochrane Database Syst Rev. 2002;(2):CD001520. doi:10.1002/14651858.CD001520
Results: Melatonin demonstrates potent antioxidant properties, protecting neurons during sleep, supporting immune function, and promoting cellular repair processes.
Citation: Reiter RJ, et al. Curr Top Med Chem. 2002;2(2):181-197. doi:10.2174/1568026023394443