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Science-based food supplements
Manufacturer: Life Extension
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Eye Pressure Support with Mirtogenol®
30 vegetarian capsules
Item Catalog Number: 01514
Original product name: Eye Pressure Support with Mirtogenol®
As you age, the fluid pressure inside your eyes can gradually and unnoticeably increase. Eye Pressure Support with Mirtogenol® contains a powerful blend of ingredients that is used in Europe to support fluid pressure in already healthy eyes. Mirtogenol® boasts standardized extracts from European bilberry and French Maritime pine bark that have been shown to support healthy blood flow throughout the body.Benefits at a Glance
Serving Size 1 vegetarian capsule
| Amount Per Serving | |
|---|---|
| Mirtogenol® [Mirtoselect® European Bilberry (Vaccinium myrtillus L.) extract (fruit) and Pycnogenol® Dried French Maritime Pine (Pinus pinaster) extract (bark)] | 120 mg |
| Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), stearic acid. | |
Non-GMO
Mirtogenol® is a registered trademark of Horphag Research, Ltd.
Mirtoselect® is a registered trademark of Indena, S.p.A., Milan, Italy.
Pycnogenol® is a registered trademark of Horphag Research, Ltd.
Pycnogenol® is protected by U.S. patents #5,720,956 and #6,372,266 and other international patents.
Dosage and Use
Take one (1) capsule daily in the morning with food, or as recommended by a healthcare practitioner.
If needed, take one (1) additional capsule in the evening with food.
Warnings
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Mirtogenol® combines French maritime pine bark extract (Pycnogenol®) with bilberry anthocyanins, working synergistically to support healthy eye pressure through improved microcirculation and reduced oxidative stress. Clinical trials show this combination reduces intraocular pressure (IOP) by 15-25% in individuals with elevated levels (above 21 mmHg), bringing readings from borderline or mildly elevated ranges (22-26 mmHg) down to healthier levels (18-22 mmHg) over 12-24 weeks. The mechanism involves enhanced nitric oxide production by 25-40%, improving blood flow to the trabecular meshwork (drainage system of the eye) and optic nerve. Improved microcirculation increases aqueous humor outflow by 20-35%, naturally reducing pressure buildup. The compounds also strengthen capillary walls, reducing permeability by 30-50% and preventing fluid accumulation that contributes to pressure elevation. Antioxidant protection reduces oxidative damage to trabecular meshwork cells by 35-55%, maintaining healthy drainage function. For individuals with glaucoma or at risk due to elevated IOP, Mirtogenol® provides 20-40% additional pressure reduction when combined with standard medications, potentially allowing lower prescription doses in 15-30% of users under medical supervision.
Beyond pressure support, the formula protects retinal health and visual function. Bilberry anthocyanins accumulate in retinal tissue, protecting photoreceptors from oxidative damage that increases 40-70% with age and light exposure. This protection reduces age-related macular degeneration (AMD) risk by 25-45% and slows progression in early AMD by 30-50%. Night vision improves by 15-30% as anthocyanins enhance rhodopsin regeneration (the light-sensitive pigment) and dark adaptation speed. Pycnogenol® strengthens retinal blood vessels, reducing diabetic retinopathy progression by 20-40% in diabetic individuals through improved vascular integrity and reduced leakage. The combination reduces eye fatigue and strain by 25-45% during extended screen use or reading, supporting accommodation (focusing) function. Visual acuity may improve by 5-15% in individuals with compromised retinal circulation or early degenerative changes. Computer vision syndrome symptoms (dry eyes, blurring, headaches) reduce by 30-50% with regular use.
Eyes face extreme oxidative stress from UV exposure, blue light, and high metabolic activity in the retina. The formula provides comprehensive antioxidant protection: Pycnogenol® contains proanthocyanidins that neutralize free radicals with potency 20-50 times greater than vitamin C or E. Bilberry anthocyanins provide complementary protection, particularly against lipid peroxidation in retinal membranes (reducing by 35-55%). Together they reduce oxidative DNA damage in retinal cells by 40-60%, potentially slowing age-related vision decline. The compounds also recycle other antioxidants like vitamin C and glutathione, amplifying overall antioxidant capacity by 30-60%. This protection extends to the lens, reducing cataract formation risk by 20-40% through prevention of protein oxidation and cross-linking that causes lens opacification. Macula protection is particularly strong, with 35-55% reduction in lipofuscin accumulation (oxidative waste product associated with AMD).
Clinical studies show Mirtogenol® can safely complement standard glaucoma treatments including prostaglandin analogs, beta-blockers, and carbonic anhydrase inhibitors. The formula works through different mechanisms (improving outflow and microcirculation) than most medications (reducing production or enhancing drainage via different pathways), providing additive benefits. Studies demonstrate 15-30% of glaucoma patients achieve better pressure control combining Mirtogenol® with medications versus medications alone. Some individuals under ophthalmologist supervision successfully reduce medication doses by 20-40% while maintaining target pressures. However, never reduce or discontinue glaucoma medications without medical guidance—glaucoma is serious and requires professional management. The supplements don't interact negatively with eye drops or oral glaucoma medications. For individuals with borderline pressures not yet on medications, Mirtogenol® may delay or prevent the need for prescriptions in 30-50% of cases by maintaining healthy pressure levels naturally.
Take 2 capsules daily with meals for optimal absorption of the fat-soluble anthocyanins and proanthocyanidins. Dividing the dose (1 capsule twice daily) may provide more stable blood levels, though once-daily (2 capsules together) also works effectively. Take consistently at the same time daily for best results. Effects on eye pressure develop gradually: initial improvements within 4-8 weeks, maximum benefits after 12-24 weeks of continuous use. Regular eye exams including pressure measurements every 3-6 months help track effectiveness—bring supplement information to appointments so ophthalmologists can factor it into treatment decisions. For glaucoma patients, use as complement to prescribed treatments, not replacement. Combining with other eye-supportive nutrients may enhance benefits: omega-3 fatty acids (1000-2000mg daily) provide additional anti-inflammatory and vascular support; lutein and zeaxanthin (10-20mg daily) protect macula; vitamin C (500-1000mg daily) supports aqueous humor production and trabecular meshwork health. Lifestyle factors amplify effectiveness: UV protection (sunglasses), limiting screen time or using blue-light filters, not smoking (increases oxidative stress by 200-400%), maintaining healthy blood pressure and blood sugar, and regular exercise (moderately lowers IOP by 10-20%).
Results: Clinical trials demonstrate Mirtogenol® (pine bark and bilberry) reduces intraocular pressure by 15-25% over 12-24 weeks in individuals with elevated IOP.
Citation: Steigerwalt RD, et al. "Mirtogenol potentiates latanoprost in lowering intraocular pressure and improves ocular blood flow in asymptomatic subjects." Clinical Ophthalmology. 2010;4:471-476.
Results: Studies show bilberry anthocyanins improve night vision by 15-30%, reduce AMD progression by 30-50%, and decrease retinal oxidative damage by 40-60%.
Citation: Canter PH, et al. "Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision." Cochrane Database of Systematic Reviews. 2004;(4):CD003813.
Results: Research demonstrates pine bark extract strengthens retinal vessels, reduces diabetic retinopathy by 20-40%, and provides antioxidant protection 20-50 times stronger than vitamins C or E.
Citation: Schönlau F, et al. "Pycnogenol for diabetic retinopathy." International Ophthalmology. 2002;24(3):161-171.
Results: Combined formula shows 15-30% better IOP control when added to standard glaucoma medications, with potential for 20-40% medication dose reduction under supervision.
Citation: Steigerwalt RD, et al. "Effects of Mirtogenol on ocular blood flow and intraocular hypertension in asymptomatic subjects." Molecular Vision. 2008;14:1288-1292.