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Science-based food supplements
Manufacturer: Life Extension
In stock
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Mega EPA/DHA
120 softgels
Item Catalog Number: 01937EU
The body needs fatty acids to survive and is able to make all but two of them: linoleic acid (LA), in the omega-6 family, and alpha-linolenic acid (ALA) in the omega-3 family. These two fatty acids must be supplied by the diet and are therefore considered essential fatty acids (EFAs).Serving Size 2 softgels
Servings Per Container 60
| Amount per day (4 capsules) | |
|---|---|
|
Fish Oil Concentrate Yielding: EPA (eicosapentaenoic acid) 1440 mg DHA (docosahexaenoic acid) 960 mg |
4000 mg |
| Ingredients: Highly refined fish oil concentrate (Wild anchovy), fish gelatine (tilapia), humectant (glycerol), purified water, natural lemon flavour, antioxidant (extracts of rosemary) | |
Non-GMO
Dosage and Use
Take two (2) softgels one to two times daily with meals.
Caution
If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.
Warnings
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Mega EPA/DHA provides exceptionally high concentrations of omega-3 fatty acids in each softgel, delivering therapeutic doses in fewer capsules than standard fish oil. While typical fish oil contains 30% omega-3s, this concentrated formula provides significantly higher EPA and DHA per serving. The fish oil undergoes molecular distillation and purification to remove contaminants while concentrating beneficial omega-3s. This high-potency approach means you get maximum cardiovascular, brain, and anti-inflammatory benefits without taking multiple large capsules daily. The concentrated formula also reduces the fishy aftertaste and digestive upset some people experience with lower-quality fish oils.
EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are distinct omega-3 fatty acids with complementary but different roles. EPA primarily supports cardiovascular health, healthy inflammatory response, and mood regulation by serving as a precursor to anti-inflammatory compounds called resolvins. DHA is the predominant structural omega-3 in the brain and retina, essential for cognitive function, memory, vision, and nervous system development and maintenance. Both are critical because human bodies cannot efficiently convert plant-based omega-3s (ALA) into EPA and DHA. Mega EPA/DHA provides generous amounts of both for comprehensive health support throughout the body.
Omega-3s from fish oil support heart health through multiple mechanisms. EPA and DHA help maintain healthy triglyceride levels already within normal range by reducing hepatic triglyceride synthesis. They support healthy blood pressure by promoting vascular relaxation and endothelial function. Omega-3s help maintain healthy heart rhythm and support proper platelet function without excessive clotting. They reduce inflammatory markers associated with cardiovascular concerns and support healthy cholesterol particle size and composition. Clinical studies show regular omega-3 supplementation at therapeutic doses significantly reduces cardiovascular risk factors and supports overall heart health maintenance.
Molecular distillation is a purification process that removes environmental contaminants including heavy metals like mercury, PCBs, and dioxins that can accumulate in fish. This process uses vacuum and heat to separate omega-3s from contaminants based on molecular weight differences, ensuring the final product meets or exceeds stringent purity standards. Mega EPA/DHA undergoes rigorous testing and certification for purity and freshness. The process also helps concentrate omega-3 content while removing oxidized lipids that contribute to fishy taste and smell. This results in a cleaner, safer, more effective fish oil supplement free from the contaminants of concern in ocean fish.
For best results, take Mega EPA/DHA with meals containing dietary fat, which significantly enhances omega-3 absorption. You can take the daily dose all at once or split between meals based on preference. Taking with food also minimizes any potential fishy aftertaste or digestive upset. Consistency is crucial—omega-3s accumulate in cell membranes and tissues over time, with maximum cardiovascular and anti-inflammatory benefits appearing after 2-3 months of regular daily use. Store in a cool place or refrigerate to maintain freshness and prevent oxidation. Consider taking with vitamin E or other antioxidants for additional protection of the delicate omega-3 fatty acids.
Results: Clinical trials demonstrate high-dose EPA and DHA supplementation significantly reduces triglyceride levels by 25-35%, with concentrated omega-3 formulas providing superior lipid-lowering effects compared to standard fish oil in patients with elevated triglycerides.
Citation: Skulas-Ray AC, et al. Circulation. 2019 Nov;140(25):e673-e691.
Results: Research shows regular omega-3 supplementation supports healthy blood pressure, with meta-analyses indicating reductions of 3-5 mmHg systolic and 2-3 mmHg diastolic pressure, particularly in individuals with hypertension or prehypertension metabolic concerns.
Citation: Miller PE, et al. Am J Hypertens. 2014 Jul;27(7):885-96.
Results: Studies demonstrate DHA supplementation supports cognitive function and memory, with clinical trials showing improvements in working memory, processing speed, and cognitive performance in adults with lower baseline omega-3 status over 6-month supplementation periods.
Citation: Stonehouse W, et al. Am J Clin Nutr. 2013 May;97(5):1134-43.
Results: Clinical research indicates high-dose omega-3 supplementation reduces inflammatory biomarkers including C-reactive protein, interleukin-6, and TNF-alpha by 20-40%, supporting healthy inflammatory response and reducing systemic inflammation associated with chronic disease.
Citation: Li K, et al. J Am Coll Nutr. 2014;33(6):406-14.