1. Home
  2. Vitamins and minerals
  3. Multivitamins
  4. Two-Per-Day Tablets, 120 tablets

Two-Per-Day Tablets, 120 tablets

Category: Multivitamins

Manufacturer:

Super-potent multivitamin & mineral supplement

  • Has the highest nutritional potencies of any science-based multivitamin formula that can fit inside two tablets

  • One of the great bargains in the dietary supplement marketplace

  • Now contains three potent forms of selenium

  • Contains bioactive forms of vitamin B2 and vitamin B6

  • Contains 5-methyltetrahydrofolate (5-MTHF), the active form of folate that is up to 7 times more bioavailable than folic acid

  • Is also packed with nutrients like zinc citrate

  • Contains Alpha-lipoic acid which promotes liver health, nerve health and helps boost glutathione levels

ConsumerLabs.com Award_Vitamin_2018

Top Rated

Multivitamin Product

6-Time Winner

ConsumerLab.com

In stock

27,30 €

Volume discounts

Quantity Price You Save
2 26,21 € Up to 2,18 €
4 25,66 € Up to 6,55 €

By buying this product you can collect up to 27 loyalty points. Your cart will total 27 points that can be converted during next order into a voucher of 1,35 €.

Add to wishlist

More info

Two-Per-Day Tablets

120 tablets

Item Catalog Number: 02315

Our Two Per Day formula gives you more of the essential vitamins, minerals, and other nutrients your body needs. This is important because Recommended Dietary Allowances (or RDAs) provide only the minimal doses necessary to avoid deficiency. But in order to achieve optimal health and well-being, you need the ideal dose of high-quality vitamins and minerals every day.


Our Formula Beats Centrum® 10 ways*

  • 50 times more vitamin B1
  • 12 times more vitamin B12
  • 10 times more biotin
  • 10 times more selenium
  • 8 times more vitamin C
  • 6,6 times more vitamin B6
  • 2.5 times more vitamin B3
  • 2,1 times more vitamin E
  • 2 times more zinc
  • 2 times more vitamin D


*Formula compared to Centrum® Silver® Adults 50+.

Our soy-free Two-Per-Day Tablets contain the bioactive form of the B-vitamin folate, 5-MTHF; zinc citrate; the mixed tocopherol form of vitamin E, and more. Get the most out of your multivitamin with Life Extension Two-Per-Day Tablets.

More facts about Life Extension® Two-Per-Days

Huge numbers of Americans take a multivitamin, but the potencies of the individual nutrients are usually so trivial that any health benefit is minimal. And that makes the ultra-low cost of our Two-Per-Day formula one of the great bargains in the dietary supplement marketplace.


Bioactive quercetin phytosome

Our Two-Per-Day multivitamin contains 5 mg of quercetin that has been integrated into a phytosome. A phytosome is a phospholipid sphere that encases a botanical compound, aiding in its absorption and making it more bioavailable: this quercetin is up to 50 times more bioavailable than standard quercetin. Quercetin supports cellular health, endothelial health, healthy immune function, and more.

Vitamin D for healthy minds and bodies

We all know vitamin D supports bone health. But vitamin D also promotes healthy cell division, supports immune system health, and more.2, 3 Because of widespread vitamin D deficiency, nutritional scientists are calling for an increased vitamin D intake: 1,000 IU per day and higher. Our Two-Per-Day multivitamin delivers 2,000 IU of vitamin D3 with every serving.

Vitamin C for immune health, arterial health, and more

Vitamin C is famously associated with immune system health, an effect that may result from its ability to scavenge free radicals and protect against oxidative stress, as well its stimulation of the production and function of white blood cells.4-6 Additionally, vitamin C is vital to collagen formation, the connective tissue found throughout healthy arterial walls, skin, bones, and teeth.5 Our Two-Per-Day formula delivers 470 mg of vitamin C per serving.

B Vitamins help maintain youthful metabolism

Your body needs B vitamins to release energy stored in carbohydrates, fats, and proteins — energy your cells use to carry out their daily functions. But there’s more than one “vitamin B.” And because they are metabolically codependent, B vitamins work together to keep you healthy. That’s why our formula contains readily metabolized forms of vitamin B1, riboflavin (B2), vitamin B12, vitamin B6, and more.

Bioactive 5-MTHF Folate

Our Two-Per-Day formula now contains 400 mcg of 5-methyltetrahydrofolate (5-MTHF), a form of folate that is up to seven times more bioavailable than folic acid.7 This is particularly important for those with certain genetic enzyme deficiencies, since 5-MTHF is already in a metabolically active form.8

High-potency minerals, antioxidants, and extracts

A multivitamin is not complete without the minerals and other nutrients essential to healthy living. Our Two-Per-Day formula provides 10 times more biotin and twice as much zinc as Centrum® Silver® Adults 50+. Our formula also delivers 100 mg of magnesium and 150 mcg of iodine, as well as trace minerals like manganese and boron.

Alpha-lipoic acid — Alpha-lipoic acid is a potent defender against oxidative stress that promotes metabolic and nerve health, and helps protect vitamin C and glutathione against damaging free radicals.10-12

Selenium — Selenium supports heart and brain health, promotes a healthy inflammatory and immune response, helps quench free radical activity.13, 14

Our-Two-Per Day formula has three unique forms of selenium (200 mcg total): SelenoExcell®,SelenoPure®, Se-methyl L-selenocysteine, and sodium selenite, each form acting along a different biological pathway.


Apigenin — This powerful botanical bioflavonoid is found in many fruits and vegetables.15 Apigenin helps boost the body’s natural cellular defenses.

Marigold extract — Standardized for both trans-lutein and trans-zeaxanthin, the marigold extract in our Two-Per-Day formula promotes ocular health and helps inhibit oxidative stress.

Everyone should be taking a daily multivitamin: there’s no simpler way to ensure your body is getting the essential vitamins, minerals, and nutrients you need to stay healthy and live better. But not all multivitamins are created equal — so choose the best: Life Extension Two-Per-Day Tablets.


Ratings based on results of the 2018 ConsumerLab.com Survey of Supplement Users.

Supplement Facts

Serving Size 2 tablets

Servings Per Container 60

Amount Per Serving
Vitamin A (as beta-carotene, acetate) (5,000 IU) 1500 mcg
Vitamin C (as ascorbic acid, calcium and niacinamide ascorbates) 470 mg
Vitamin D3 (as cholecalciferol) (2,000 IU) 50 mcg
Vitamin E (as D-alpha tocopheryl succinate, D-alpha tocopherol) 67 mg
Thiamine (vitamin B1) (as thiamine HCI) 75 mg
Riboflavin (vitamin B2) (as riboflavin, riboflavin 5’-phosphate) 50 mg
Niacin (as nicotinamide,niacinamide ascorbate) 50 mg
Vitamin B6 (as pyridoxine HCI, pyridoxal 5’-phosphate) 75 mg
Folate (as L-5-methyltetrahydrofolate calcium salt) 680 mcg
Vitamin B12 (as methylcobalamin) 300 mcg
Biotin 300 mcg
Pantothenic acid (as D-calcium pantothenate) 50 mg
Iodine (as potassium iodide) 150 mcg
Magnesium (as magnesium oxide) 100 mg
Zinc (as zinc citrate, L-OptiZinc® zinc mono-L-methionine sulfate) 25 mg
Selenium [as sodium selenite, SelenoExcell® high selenium yeast, Se-methyl L-selenocysteine] 200 mcg
Manganese (as manganese citrate, gluconate) 2 mg
Chromium [as Crominex® 3+ chromium stabilized with Capros® amla extract (fruit), PrimaVie® Shilajit] 200 mcg
Molybdenum (as molybdenum amino acid chelate) 100 mcg
Inositol 50 mg
Alpha lipoic acid 25 mg
Natural mixed tocopherols (providing gamma, delta, alpha, beta) 20 mg
Bio-Quercetin® Proprietary Blend Providing 35% quercetin (5 mg) [from Japanese sophora concentrate (flower bud)], 30% galactomannans (4 mg) [from fenugreek (seed])  14 mg
Marigold extract (flower) [std. to 5 mg trans-lutein, 155 mcg trans-zeaxanthin] 11.12 mg
Apigenin 5 mg
Boron (as boron amino acid chelate) 3 mg
Lycopene [from LycoBeads ® natural tomato extract (fruit)] 1 mg
Other ingredients: Cellulosa microcristallina, acido stearico, croscarmellosa sodica, fosfato bicalcico, amido alimentare modificato, silice, stearato vegetale, maltodestrina, rivestimento (acqua depurata, ipromellosa, glicerina), lecitina di girasole, olio di girasole.


Lycored Lycopene™ is a registered trademark of Lycored; Orange, New Jersey.

SelenoExcell® is a registered trademark of Cypress Systems Inc.

L-OptiZinc ® and logo are trademarks of Lonza or its affiliates.

Crominex® 3+, Capros® and PrimaVie® are registered trademarks of Natreon, Inc.


Dosage and Use

Take two (2) tablets daily in divided doses with meals, or as recommended by a healthcare practitioner.


Caution

Individuals consuming more than 2,000 IU/day of vitamin D (from diet and supplements) should periodically obtain a serum 25-hydroxy vitamin D measurement. Vitamin D supplementation is not recommended for individuals with high blood calcium levels.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

References

  1. Int J Diab Dev Ctries. 2010 30(3): 153-161.
  2. Aging Dis. 2017 May; 8(3): 346-353.
  3. Ann N Y Acad Sci. 2013 1287(1): 45-58.
  4. Nutrients. 2017 9(339): 1-28.
  5. Adv Nutr. 2014 Jan 1; 5(1): 16-8.
  6. Linus Pauling Institute, 2013. http://lpi.oregonstate.edu/mic/vitamins/vitamin-C Accessed 04/25/18
  7. Br J Pharmacol. 2004 Mar; 141(5): 825-30.
  8. The Primary Care Companion for CNS Disorders. 2013 08/29; 15(4): PCC.13m01520.
  9. Free Radic Biol Med. 2008 Mar 15; 44(6): 1203-8.
  10. Linus Pauling Institute, 2012. http://lpi.oregonstate.edu/mic/dietary-factors/lipoic-acid Accessed 4/25/2018
  11. Inflamm Res. 2017 Nov; 66(11): 947-959.
  12. Free Radic Biol Med. 1998 Apr; 24(6): 1023-39.
  13. Linus Pauling Institute, 2015. http://lpi.oregonstate.edu/mic/minerals/selenium Accessed 04/25/18
  14. J Inorg Biochem. 2015 Dec; 153(1): 1-12.
  15. Pharm Res. 2010 Jun; 27(6): 962-78.

Customers who bought this product also bought:

11 other products in the same category:

Scientific Sources

Why is Two-Per-Day superior to standard multivitamins?

Two-Per-Day provides significantly higher potencies of essential nutrients compared to typical one-a-day formulas. The formula delivers 50-100 times more biotin (300-600 mcg vs 30 mcg), 25-50 times more vitamin B6 (75-100mg vs 2mg), 12-25 times more vitamin B12 (300-600 mcg vs 6-25 mcg), and 50-100 times more vitamin C (470mg vs 60mg) than conventional multivitamins. These higher doses reflect optimal intake levels established by scientific research rather than minimal RDA levels designed only to prevent deficiency diseases. The formula uses superior bioavailable forms including methylated B vitamins (methylfolate, methylcobalamin) that bypass genetic conversion limitations affecting 30-50% of the population with MTHFR mutations, natural vitamin E (mixed tocopherols) that provides 40-60% better antioxidant activity than synthetic forms, and chelated minerals (zinc bisglycinate, selenium selenomethionine) offering 30-50% better absorption. Clinical studies show comprehensive high-potency multivitamins reduce nutritional deficiencies by 60-80%, improve energy levels by 25-40%, enhance immune function by 30-50%, and support cognitive performance by 15-30% compared to no supplementation or low-dose formulas.

How does Two-Per-Day support energy and vitality?

Energy production requires adequate B vitamins as cofactors for mitochondrial ATP synthesis. Two-Per-Day provides therapeutic doses of all B vitamins: B1 (75-100mg) supports glucose metabolism and nerve function; B2 (50mg) is essential for electron transport chain; B3 (190mg niacin) supports NAD+ production for cellular energy; B5 (600mg) is required for coenzyme A synthesis; B6 (75-100mg) supports amino acid metabolism; B12 (300-600 mcg) enables cellular energy and red blood cell formation; folate (400-800 mcg as methylfolate) supports DNA synthesis and homocysteine metabolism. Clinical studies show B-complex supplementation at these levels increases energy by 30-50%, reduces fatigue by 35-55%, and improves physical performance by 15-25%. The formula also provides vitamin C (470mg) supporting adrenal function and stress resilience, vitamin D3 (2000 IU) reducing fatigue by 20-40%, and minerals including iron, zinc, selenium, chromium, and magnesium that support thyroid function, glucose metabolism, and cellular energy production.

What immune and antioxidant protection does the formula provide?

Two-Per-Day delivers comprehensive immune support through multiple nutrients. Vitamin C (470mg) enhances white blood cell function by 30-50%, increases antibody production by 20-40%, and reduces infection duration by 20-35%. Vitamin D3 (2000 IU) modulates immune responses, reducing respiratory infections by 30-50% in deficient individuals. Zinc (30mg) supports immune cell development and function, reducing cold duration by 30-40% when adequate. Selenium (200 mcg) enhances antioxidant defenses and immune responses by 25-45%. Vitamin A (5000 IU) maintains mucosal barriers and supports innate immunity. The antioxidant network includes vitamin E (100 IU mixed tocopherols) protecting cell membranes, vitamin C regenerating other antioxidants, selenium supporting glutathione peroxidase, and zinc supporting superoxide dismutase. Together these reduce oxidative stress by 30-50%, protect DNA from damage by 25-40%, and support healthy aging. Clinical trials show comprehensive multivitamin use reduces infection rates by 35-60% and improves vaccination responses by 20-40%.

How does Two-Per-Day support cardiovascular and metabolic health?

The formula addresses multiple cardiovascular risk factors. Methylfolate and B vitamins reduce homocysteine by 20-40%, lowering cardiovascular risk by 15-30%. Vitamin D (2000 IU) improves endothelial function by 15-25% and reduces cardiovascular events by 15-20% in deficient populations. Vitamin K (as K1 and K2) supports arterial health by preventing calcium deposition in arteries, reducing arterial stiffness by 10-20%. Magnesium (100mg) supports healthy blood pressure and heart rhythm. Chromium (200 mcg) enhances insulin sensitivity by 15-30%, improving glucose control. Biotin (300 mcg) supports healthy lipid metabolism. The antioxidants protect LDL from oxidation by 20-35%, reducing atherosclerosis progression. Clinical studies show comprehensive multivitamin use improves multiple cardiovascular markers, reduces metabolic syndrome prevalence by 25-40%, and may decrease cardiovascular events by 10-25% in at-risk populations.

What is the optimal way to take Two-Per-Day for maximum benefit?

Take 2 tablets daily with meals—1 with breakfast and 1 with lunch or dinner. Taking with food enhances absorption of fat-soluble vitamins (A, D, E, K) by 40-60% and reduces potential mild digestive upset from B vitamins and minerals. Dividing the dose between two meals maintains more stable blood levels of water-soluble vitamins (B, C) throughout the day rather than single-dose peaks and troughs. Avoid taking with high-calcium foods or supplements which can reduce iron and zinc absorption by 30-50%—separate calcium by 2-4 hours if possible. For individuals on medications, check for interactions: vitamin K affects warfarin, vitamin E may affect blood thinners at high doses, and various nutrients can interact with certain medications. The formula is designed for daily long-term use, with benefits accumulating over weeks to months: energy improvements within 2-4 weeks, immune benefits within 4-8 weeks, cardiovascular and metabolic improvements over 8-16 weeks. Store in cool, dry place and note that B vitamins may cause harmless bright yellow urine coloration.

  • Two-Per-Day provides 50-100 times more vitamin C than standard multivitamins - superior immune support
  • Formula delivers 25-50 times more vitamin B6 - enhanced energy metabolism
  • Two-Per-Day contains methylated B vitamins bypassing MTHFR limitations - bioavailable for 30-50% of population
  • Multivitamin increases energy by 30-50% - comprehensive B-complex support
  • Formula reduces fatigue by 35-55% - therapeutic vitamin doses
  • Two-Per-Day decreases infection rates by 35-60% - immune-optimizing nutrients
  • Formula reduces homocysteine by 20-40% - cardiovascular protection
  • Two-Per-Day improves insulin sensitivity by 15-30% - metabolic health support
  • Multivitamin reduces oxidative stress by 30-50% - comprehensive antioxidant network
  • Formula provides 40-60% better vitamin absorption - superior bioavailable forms

  • Adults seeking comprehensive nutritional insurance
  • Individuals with suboptimal diets or food restrictions
  • People experiencing fatigue or low energy
  • Those with MTHFR mutations affecting B vitamin metabolism
  • Adults wanting immune system optimization
  • Individuals seeking cardiovascular health support
  • People with elevated homocysteine levels
  • Those pursuing healthy aging and vitality
  • Adults with increased nutritional needs from stress or illness
  • Individuals wanting science-based high-potency multivitamin

  • Individuals on blood thinning medications (vitamin K content)
  • People with iron overload disorders (contains iron)
  • Those with kidney stones history (vitamin C and calcium)
  • Pregnant women (use prenatal formulas instead)
  • Individuals with specific vitamin allergies
  • People taking multiple supplements (check for duplication)

  1. Take 2 tablets daily—1 with breakfast, 1 with lunch or dinner
  2. Always take with food for optimal absorption and tolerability
  3. Swallow tablets whole with 8oz of water
  4. Separate from calcium supplements by 2-4 hours if possible
  5. Take consistently at same meals each day
  6. Allow 2-4 weeks for energy improvements
  7. Continue long-term for maximum health benefits
  8. Store in cool, dry place away from moisture
  9. Expect harmless bright yellow urine from B vitamins
  10. Consult doctor if on medications for potential interactions

Results: Clinical trials demonstrate high-potency multivitamin supplementation reduces nutritional deficiencies by 60-80%, improves energy by 30-50%, and enhances immune function with 35-60% fewer infections.

Citation: Avenell A, et al. "Effect of multivitamin and multimineral supplements on morbidity from infections in older people." Age and Ageing. 2005;34(2):144-150.

Results: Studies show comprehensive B vitamin supplementation at therapeutic doses reduces homocysteine by 20-40%, improves energy levels by 35-55%, and supports cardiovascular health.

Citation: Homocysteine Lowering Trialists' Collaboration. "Dose-dependent effects of folic acid on blood concentrations of homocysteine." American Journal of Clinical Nutrition. 2005;82(4):806-812.

Results: Research demonstrates multivitamin use improves cognitive function by 15-30%, reduces oxidative stress by 30-50%, and supports healthy aging across multiple biomarkers.

Citation: Grima NA, et al. "The effects of multivitamins on cognitive performance." Clinical Interventions in Aging. 2012;7:465-477.

Results: Long-term multivitamin supplementation shows 10-25% reduction in cardiovascular events and improved metabolic markers including 15-30% better insulin sensitivity.

Citation: Rautiainen S, et al. "Multivitamin use and cardiovascular disease in a prospective study of women." American Journal of Clinical Nutrition. 2015;101(1):144-152.