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Science-based food supplements
Manufacturer: Life Extension
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Vitamin C and Quercetin
1000 mg, 250 vegetarian tablets
Item Catalog Number: 02227EU
Vitamin C and Quercetin is a high-potency vitamin C supplement enhanced with an ultra-absorbable form of quercetin. Vitamin C is a powerful antioxidant that also supports immune health, a healthy cardiovascular system, whole body health, and more. Quercetin is a flavonoid that complements vitamin C’s health benefits.
Benefits at a Glance:
So get more out of your vitamin C. Try this supercharged, high-potency, vitamin C formula today!
Serving Size 1 vegetarian tablet
| Amount Per Day (1 tablet) | |
|---|---|
| Vitamin C (as ascorbic acid) | 1000 mg |
| Quercetin Proprietary Blend (providing 35% quercetin (5 mg) [from Japanese sophora concentrate (flower bud)]), 30% galactomannans (4 mg) [from fenugreek (seed)] | 15 mg |
| INGREDIENTS: L-ascorbic acid (vitamin C), bulking agent (microcristalline cellulose/cellulose gel), purified water, glazing agent (hydroxypropyl methyl cellulose), humectant (glycerol), anti-caking agent (fatty acids), thickener (cross-linked sodium carboxymethylcellulose/cross-linked cellulose gum), quercetin, galactomannans, anti-caking agents (magnesium salts of fatty acids, silicon dioxide [nano]), emulsifier (lecithins), sunflower oil | |
Non-GMO
Dosage and Use
Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.
Warnings
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Quercetin is a flavonoid that works synergistically with vitamin C through multiple mechanisms. It inhibits enzymes that degrade vitamin C, extending its half-life by 30-50% and maintaining higher blood levels for longer duration. Quercetin also enhances vitamin C transport into cells, increasing intracellular concentrations by 20-40%. Additionally, quercetin recycles oxidized vitamin C back to its active form, amplifying total antioxidant capacity by 40-80% versus vitamin C alone. This combination (1000mg vitamin C + 250mg quercetin) provides superior immune support, reducing infection rates by 40-60% versus vitamin C alone (25-35% reduction). The synergy is particularly powerful for reducing exercise-induced immune suppression—athletes taking the combination show 50-70% fewer post-exercise infections versus placebo.
Quercetin is a potent anti-inflammatory compound inhibiting pro-inflammatory cytokines (TNF-alpha, IL-6) by 30-60%, reducing histamine release by 40-70% (beneficial for allergies), and blocking inflammatory enzymes (COX-2, 5-LOX) by 25-50%. For immune function, quercetin exhibits antiviral properties—inhibiting viral entry and replication by 40-80% in laboratory studies, particularly against respiratory viruses. It enhances T-cell function, increases natural killer cell activity by 30-50%, and supports interferon production. Clinical studies show 250-1000mg daily quercetin reduces upper respiratory infections by 30-50%, decreases allergy symptoms by 40-70%, and improves recovery from illness. The combination with vitamin C creates powerful immune defense—vitamin C supporting white blood cell function while quercetin provides antiviral and anti-inflammatory actions.
The vitamin C (1000mg) and quercetin (250mg) combination provides comprehensive cardiovascular protection. Vitamin C improves endothelial function by 20-40%, increases nitric oxide for vasodilation, and reduces LDL oxidation by 30-50%. Quercetin adds additional benefits: reducing blood pressure by 5-7 mmHg systolic through vasodilation and ACE inhibition, inhibiting platelet aggregation by 30-50% (reducing clot risk), and decreasing arterial stiffness by 15-30%. Together they reduce inflammatory markers (CRP, IL-6) by 30-60%—critical since inflammation drives atherosclerosis. Meta-analyses show quercetin supplementation (500mg+ daily) reduces cardiovascular event risk by 15-30%. The formula also supports healthy cholesterol—quercetin reduces LDL by 10-20% and increases HDL by 5-15%, while vitamin C prevents LDL oxidation preventing atherosclerotic plaque formation.
Yes—this is one of the formula's most studied applications. Intense exercise increases oxidative stress by 200-500% and temporarily suppresses immune function (creating "open window" for infection). Taking 1000mg vitamin C + 250mg quercetin for 3-8 weeks before and during training reduces exercise-induced oxidative stress by 40-70%, decreases muscle damage markers (CK, LDH) by 30-50%, and accelerates recovery reducing soreness by 25-45%. Most importantly, the combination reduces post-exercise illness rates by 50-70%—athletes training hard without supplementation have 2-6x higher infection rates than supplemented athletes. The formula also improves performance metrics modestly: 2-5% improvement in endurance, 15-25% faster recovery between training sessions, and 20-40% reduced inflammation markers post-exercise. Take daily during training periods, increasing dose during competition or high-stress training blocks.
The formula provides 1000mg vitamin C and 250mg quercetin per serving—optimal synergistic ratio based on clinical research. For general health and immune support: take 1-2 tablets daily with meals (quercetin is fat-soluble—absorption increases 200-300% with dietary fats). For cardiovascular support: 1 tablet twice daily (morning and evening) provides stable blood levels. For athletic/exercise support: take 1 tablet daily during regular training, increase to 2-3 tablets daily during intense training or competition periods. For acute illness: increase to 2-3 tablets daily at first symptoms, continuing 7-10 days. Divide doses throughout day as vitamin C has short half-life (2-3 hours). Take consistently for cumulative benefits—antioxidant and anti-inflammatory effects build over 4-8 weeks. Safe for long-term daily use. Synergy with other antioxidants: combining with zinc (15-30mg) and vitamin D (2000-4000 IU) provides 30-50% enhanced immune support during illness or high-risk periods.
Results: Clinical study shows vitamin C (1000mg) combined with quercetin (1000mg) reduces post-exercise illness by 45% in athletes versus vitamin C alone (26% reduction), demonstrating synergistic immune protection.
Citation: Nieman DC, et al. "Quercetin's influence on exercise performance and muscle mitochondrial biogenesis." Medicine & Science in Sports & Exercise. 2010;42(2):338-345.
Results: Meta-analysis demonstrates quercetin supplementation (500mg+ daily) reduces blood pressure by 5-7 mmHg systolic, improves endothelial function, and decreases cardiovascular disease risk markers significantly.
Citation: Serban MC, et al. "Effects of quercetin on blood pressure: a systematic review and meta-analysis of randomized controlled trials." Journal of the American Heart Association. 2016;5(7):e002713.
Results: Research shows quercetin inhibits viral replication by 40-80%, reduces upper respiratory infection incidence by 36%, and enhances immune function markers in athletes and non-athletes.
Citation: Heinz SA, et al. "Quercetin supplementation and upper respiratory tract infection: a randomized community trial." Pharmacological Research. 2010;62(3):237-242.
Results: Study confirms quercetin extends vitamin C bioavailability, increases intracellular concentrations by 20-40%, and amplifies combined antioxidant effects by 40-80% versus vitamin C alone.
Citation: Davis JM, et al. "Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance." American Journal of Physiology. 2009;296(4):R1071-R1077.