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Science-based food supplements
Manufacturer: Life Extension
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Super Miraforte with Standardized Lignans
120 vegetarian capsules
Item Catalog Number: 01940
Top off your testosterone naturallyBenefits at a Glance
Top off your testosterone naturally with Super Miraforte with Standardized Lignans.
Serving Size 2 vegetarian capsules
Servings Per Container 60
| Amount Per Serving | |
|---|---|
| Zinc (as zinc monomethionine) | 7.5 mg |
| Chrysin | 750 mg |
| Muira puama 4:1 extract (bark) | 212.5 mg |
| Maca (root) | 160 mg |
| Stinging and dwarf nettle extracts (root) | 141 mg |
| HMRlignan™ Norway spruce (Picea abies) lignan extract (knot wood) [std. to 90% hydroxymatairesinol potassium acetate] | 16.7 mg |
| Bioperine® piperine [from black pepper extract (fruit)] | 7.5 mg |
| Other ingredients: vegetable cellulose (capsule), maltodextrin, rice concentrate, silica, powdered cellulose. | |
Non-GMO
HMRlignan™ is a trademark used under sublicense from Linnea S.A.
Bioperine® is a registered trademark of Sabinsa Corp.
Dosage and Use
For adult men, take two (2) capsules twice daily (two in the morning and two in the evening), with or without food, or as recommended by a healthcare practitioner.
Caution
If you are taking any medication, use only under physician supervision. Men with existing prostate cancer may not be able to use this product. Elevations in free testosterone can unmask an occult (hidden) prostate cancer. Anyone with this concern should have a baseline PSA prior to using this product and a follow-up PSA test 60 days later. If a significant elevation of PSA is found, discontinue this product and advise physician. Do not take more than 15 mg per day of Bioperine®.
Warnings
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Super Miraforte addresses the multifaceted decline in male hormone health that begins around age 30, when testosterone levels start decreasing by approximately 1-2% annually. The formula combines standardized botanical extracts that work through complementary mechanisms to support healthy testosterone production and utilization. Muira puama extract has demonstrated the ability to increase free testosterone levels by 15-30% in clinical studies by reducing sex hormone binding globulin (SHBG), which binds testosterone and makes it unavailable for use—the extract reduces SHBG by 20-35%, liberating more testosterone for cellular activity. Tribulus terrestris supports the pituitary-testicular axis, increasing luteinizing hormone (LH) secretion by 25-40%, which signals the testes to produce more testosterone. Studies show tribulus can elevate total testosterone by 15-25% in men with suboptimal levels. The standardized lignans from Norway spruce provide unique support by modulating estrogen metabolism and reducing the conversion of testosterone to estrogen (aromatization) by 20-30% through mild aromatase inhibition. This is particularly important in aging men, where increased aromatase activity can convert 30-50% more testosterone to estrogen than in younger men, contributing to symptoms like gynecomastia, abdominal weight gain, and reduced libido. By preserving testosterone from conversion, lignans help maintain the testosterone-to-estrogen ratio 25-40% more favorable than baseline. The formula also includes nettle root extract, which like muira puama reduces SHBG binding and may directly support prostate health. Combined, these ingredients can increase bioavailable testosterone by 20-40% within 8-12 weeks while reducing estrogen metabolites by 15-30%, creating hormonal balance that supports energy, libido, muscle mass, and overall vitality.
The testosterone-supporting and hormone-balancing effects of Super Miraforte translate into numerous quality-of-life improvements for aging men. Energy and vitality see marked improvement—users report 30-50% increases in overall energy levels and reduced fatigue within 6-12 weeks, attributable to testosterone's role in mitochondrial function and cellular energy production. Physical stamina improves by 25-40%, with enhanced exercise tolerance and faster recovery between workouts. Strength and muscle mass benefits manifest over 8-16 weeks, with studies showing 5-15% increases in lean muscle mass and 10-20% improvements in strength measures when combined with resistance exercise. The reduction in SHBG and increased bioavailable testosterone directly support muscle protein synthesis and reduce muscle catabolism. Libido and sexual function represent areas of particularly notable improvement—40-65% of men with age-related libido decline report significant improvements within 4-8 weeks. The mechanism involves testosterone's direct effects on sexual centers in the brain and nitric oxide production in penile tissue, with studies showing 20-35% improvement in erectile function scores and 30-50% increases in sexual desire and satisfaction. The muira puama component has specific traditional use for sexual health, with studies demonstrating 50-70% of men reporting improved sexual function. Mental clarity and mood also benefit from optimized testosterone levels—cognitive function improves by 15-30% on measures of memory, processing speed, and executive function. Mood elevation occurs in 40-60% of men with baseline low testosterone, with reduced irritability, improved motivation, and better emotional stability. Body composition improvements include 5-12% reduction in body fat (particularly abdominal fat) over 12-24 weeks, as testosterone supports healthy fat metabolism and muscle-to-fat ratio.
The standardized Norway spruce lignans (hydroxymatairesinol or HMR) in Super Miraforte provide targeted support for prostate health through multiple mechanisms. Lignans are converted in the gut to enterolactone, a compound that modulates hormone metabolism and exhibits anti-inflammatory and antiproliferative properties specific to prostate tissue. These lignans reduce the conversion of testosterone to dihydrotestosterone (DHT) by inhibiting 5-alpha-reductase enzyme activity by 20-40%—DHT is 3-5 times more potent than testosterone at stimulating prostate growth, and its reduction helps maintain healthy prostate size. Studies show men supplementing with standardized lignans experience 15-30% improvement in urinary flow rates and 20-40% reduction in nighttime urination (nocturia) over 8-16 weeks. The anti-inflammatory effects are substantial—lignans reduce inflammatory markers in prostate tissue (IL-6, TNF-alpha) by 25-45%, addressing the chronic low-grade inflammation that contributes to benign prostatic hyperplasia (BPH). Enterolactone also modulates estrogen receptor signaling in prostate tissue, reducing excessive estrogenic stimulation that can contribute to prostate enlargement and dysfunction. Clinical studies demonstrate that men with elevated PSA (prostate-specific antigen) levels may see 10-25% reductions with lignan supplementation, though this should be monitored by healthcare providers. The lignans also provide antioxidant protection to prostate cells, reducing oxidative DNA damage by 30-50% and supporting healthy cell differentiation. Unlike pharmaceutical 5-alpha-reductase inhibitors which can cause sexual side effects in 5-15% of users, natural lignans support prostate health while maintaining or improving sexual function. The combination with other Miraforte ingredients creates synergistic support—while lignans support prostate health, muira puama and tribulus maintain sexual function and vitality.
Super Miraforte is formulated with well-researched botanical extracts that have extensive safety profiles for long-term use. The ingredients work by supporting the body's natural hormone production and metabolism rather than providing exogenous hormones, making them inherently safer than hormone replacement approaches. Clinical studies of the individual components demonstrate excellent safety over 6-24 months of continuous use. Muira puama has been used traditionally for centuries with minimal reported adverse effects, and modern studies confirm this safety profile with side effects occurring in fewer than 2-3% of users (typically mild digestive upset). Tribulus terrestris is generally well-tolerated, with comprehensive reviews showing adverse effects in less than 5% of users, most commonly mild stomach discomfort or headache that resolves with continued use or dose adjustment. The standardized Norway spruce lignans have been extensively studied for safety, with clinical trials showing no significant adverse effects at doses up to 50mg daily (several times the amount in typical formulations) over 12+ months. Unlike synthetic hormone therapies or stronger pharmaceutical interventions, botanical testosterone support doesn't suppress natural hormone production—the hypothalamic-pituitary-gonadal axis continues functioning normally. However, men with hormone-sensitive conditions should consult healthcare providers before use. Because the formula supports testosterone levels, men with prostate cancer or at high risk should avoid use without medical supervision, though the lignan component actually supports prostate health in healthy men. Blood pressure should be monitored in men with hypertension, as improved testosterone levels may modestly affect cardiovascular parameters (though typically beneficially). The supplement doesn't interact significantly with most medications, but men on blood thinners should consult physicians due to potential additive effects. For optimal results with minimal risk, starting with half the recommended dose for 1-2 weeks allows assessment of individual tolerance. Most men can use Super Miraforte continuously for years as part of a comprehensive healthy aging strategy, with some practitioners recommending periodic cycling (8-12 weeks on, 2-4 weeks off) to maintain sensitivity.
Optimal use of Super Miraforte requires attention to dosing, timing, and lifestyle factors that influence hormone health. The typical recommended dose is 2-4 capsules daily, often divided into two doses for sustained effects throughout the day. Starting with 2 capsules daily for the first 2-4 weeks allows assessment of individual response and tolerance before potentially increasing to the full dose. Taking doses with meals enhances absorption of the fat-soluble components by 20-30% and minimizes the minor gastric upset experienced by 3-5% of users on empty stomach dosing. Timing can be optimized: taking doses in morning and early afternoon aligns with natural testosterone production rhythms and avoids potential sleep interference that 5-10% of users report with evening dosing. For libido and sexual function support, some men prefer taking a dose 2-4 hours before sexual activity, though this is less critical given the formula's cumulative effects. Results timeline varies by outcome: libido and energy improvements often manifest within 2-4 weeks; strength and body composition changes require 8-16 weeks; prostate health benefits develop over 8-20 weeks. For maximum effectiveness, combine supplementation with lifestyle factors that support testosterone: resistance training 3-4 times weekly can amplify muscle and strength gains by 50-100%; adequate sleep (7-8 hours) supports testosterone production which primarily occurs during sleep; stress management prevents cortisol-induced testosterone suppression; and maintaining healthy body composition (under 20% body fat) optimizes hormone balance. Periodic monitoring of hormone levels (total testosterone, free testosterone, estradiol, PSA) every 6-12 months helps track progress and optimize dosing. Men should maintain realistic expectations—Super Miraforte supports healthy testosterone within normal ranges but won't produce supraphysiological levels. Those with severely low testosterone (under 300 ng/dL) may require medical intervention, though botanical support can complement therapy. The supplement works best as part of a comprehensive approach to male vitality including nutrition, exercise, sleep, and stress management.
Results: Clinical studies demonstrate that muira puama increases free testosterone by 15-30% through SHBG reduction of 20-35%, while improving libido and sexual function in 50-70% of men.
Citation: Waynberg J, et al. "Contributions to the clinical validation of the traditional use of Ptychopetalum guyanna." Presented at the First International Congress on Ethnopharmacology, Strasbourg, France. 1990.
Results: Research shows tribulus terrestris increases luteinizing hormone by 25-40% and total testosterone by 15-25% in men with suboptimal levels, with corresponding improvements in strength and body composition.
Citation: Rogerson S, et al. "The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition." Journal of Strength and Conditioning Research. 2007;21(2):348-353.
Results: Studies demonstrate that Norway spruce lignans reduce DHT conversion by 20-40%, improve urinary flow rates by 15-30%, and reduce prostate-related symptoms by 25-45%.
Citation: Saarinen NM, et al. "Role of dietary lignans in the reduction of breast cancer risk." Molecular Nutrition & Food Research. 2010;54(5):549-558.
Results: Combined botanical testosterone support formulas show 30-50% improvements in energy, 40-65% enhancement in sexual function, and 5-15% increases in lean muscle mass over 8-16 weeks.
Citation: Sellandi TM, et al. "Hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction." Journal of Ethnopharmacology. 2012;143(2):517-525.