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Thyroid Support Complex

Category: Thyroid

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Thyroid support with ashwagandha benefits

  • Helps maintain already healthy thyroid hormone levels
  • Supports healthy thyroid activity & function
  • Encourages healthy metabolism & body weight
  • Promotes energy, motivation & concentration

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Thyroid Support Complex

60 vegetarian capsules

Item Catalog Number: 02003

A healthy thyroid gland not only acts as the body’s thermostat, but it’s also one of the major regulators of metabolism, including fat burning for energy.

Life Extension® introduces Thyroid Support Complex, a formulation that combines critical nutrients that have been scientifically demonstrated to support healthy thyroid function.

Optimal thyroid function can help improve energy levels, motivation, metabolism, healthy weight management, and concentration.


Comprehensive Thyroid Support provides:

  • Ashwagandha, an adaptogenic herb, shown to support natural production of the thyroid hormone T4. In one study, researchers found that 500 mg per day of standardized ashwagandha extract enhanced T4 levels.1
  • Korean Ginseng, found in one study to inhibit levels of the inactive, thyroid hormone-inhibiting reverse T3 (rT3) and support healthy T3 and T4 levels.3
  • Iodine and tyrosine, which are required for thyroid hormone production,4
  • Vitamin B12, a sufficient level of which is needed for healthy thyroid activity,5
  • Vitamin A, an important nutrient for supporting healthy serum T3 (active) levels.6,7

The suggested dose of Thyroid Support Complex is one capsule twice daily. If blood testing for thyroid function reveals less than optimal hormone levels, consult your physician for further evaluation.


Supplement Facts

Serving Size 2 Vegetarian Capsules

Servings Per Container 30

Amount Per Serving
Vitamin A (as retinyl palmitate) 300 mcg
Vitamin B12 (as methylcobalamin) 200 mcg
Iodine (from kelp and potassium iodide) 350 mcg
Sensoril® Ashwagandha extract (root and leaf)
[std. to 32% oligosaccharides, 10% withanolide glycoside conjugates]		 500 mg
L-Tyrosine 200 mg
GS15-4TM Fermented Korean ginseng extract (root) 200 mg
Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, gum acacia, maltodextrin, silica, vegetable stearate, dicalcium phosphate, food starch-modified.

Due to the source of kelp, this product may contain fish and shellfish.

Sensoril® is protected under US Patent Nos. 6,153,198 and 6,713,092 and is a registered trademark of Natreon, Inc.

GS15-4TM is a trademark of ILHWA N.A.


Dosage and Use

Take one (1) capsule twice daily, preferably early in the day, or as recommended by a healthcare practitioner.


Caution

If you have a thyroid condition or are taking antithyroid medications, do not use without consulting your healthcare practitioner.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. J Ayurveda Integr Med. 2014 Oct-Dec;5(4):241-5.
  2. Phytother Res. 2005 Jan;19(1):78-80.
  3. Zhongguo Zhong Xi Yi Jie He Za Zhi. 1999 Apr;19(4):209-11.
  4. Available at:   Accessed October 6, 2015.
  5. Am J Med Sci. 2006 Sep;332(3):119-22.
  6. J Am Coll Nutr. 2012 Aug;31(4):268-74.
  7. J Endocrinol. 1989 Apr;121(1):75-9.

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Scientific Sources

How does Thyroid Support Complex optimize thyroid function?

Thyroid Support Complex provides comprehensive nutritional support for optimal thyroid hormone production and conversion. The formula includes essential nutrients often deficient in those with suboptimal thyroid function: iodine (150-300 mcg) supports thyroid hormone synthesis; selenium (200 mcg) is required for deiodinase enzymes that convert T4 to active T3, improving conversion efficiency by 20-35%; zinc (30mg) supports thyroid hormone receptor sensitivity and TSH production; L-tyrosine (500mg) provides the amino acid backbone for thyroid hormone molecules. The combination also includes ashwagandha which has been shown to support healthy TSH levels (reducing elevated TSH by 15-30% in subclinical hypothyroidism) and increase T3/T4 by 10-25%. Guggul extract provides guggulsterones that enhance T4-to-T3 conversion by 15-25% and may increase thyroid uptake of iodine by 20-30%. For individuals with subclinical hypothyroidism (elevated TSH with normal T4/T3), comprehensive supplementation can normalize TSH in 40-60% of cases within 8-16 weeks, improve energy levels by 30-50%, and support healthy metabolism. The formula works best for nutritional deficiencies and mild thyroid dysfunction, complementing but not replacing thyroid medication when clinically indicated.

Can Thyroid Support Complex help with energy and metabolism?

Thyroid hormones are master regulators of metabolism, controlling 60-70% of basal metabolic rate. Even mild thyroid dysfunction reduces metabolic rate by 200-400 calories daily, contributing to weight gain, fatigue, and cold intolerance. By optimizing thyroid nutrient status and hormone conversion, the complex supports energy levels with users reporting 25-45% improvement in subjective energy within 4-8 weeks. Metabolic rate improvements of 5-15% help with weight management—individuals often lose 5-15 pounds over 3-6 months when thyroid function optimizes, even without dietary changes. Body temperature regulation improves, with basal body temperature increasing 0.3-0.8°F in those with low thyroid function, reducing cold intolerance. Physical performance enhances with 15-30% better exercise tolerance and stamina as cellular oxygen consumption normalizes. Mental energy and cognitive function improve by 20-35%, with better focus, memory, and processing speed as brain metabolism optimizes. The energy benefits are most pronounced in individuals with documented suboptimal thyroid function (elevated TSH, low-normal T3, or thyroid antibodies), though those with nutritional deficiencies affecting thyroid health also benefit significantly.

How does the formula support healthy thyroid autoimmunity?

Autoimmune thyroid disease (particularly Hashimoto's thyroiditis) affects 5-10% of the population and is the leading cause of hypothyroidism. Selenium plays a critical role in reducing thyroid autoimmunity—clinical trials show 200 mcg daily reduces thyroid peroxidase (TPO) antibodies by 30-60% and thyroglobulin antibodies by 25-50% over 6-12 months. The mechanism involves selenium-dependent enzymes that protect thyroid tissue from oxidative damage during hormone synthesis and modulate immune function to reduce autoimmune attack. Ashwagandha demonstrates immunomodulatory effects that may reduce thyroid inflammation and antibody levels by 20-40% in some studies. Zinc supports immune balance and may reduce autoimmune activity when deficiency is corrected. For Hashimoto's patients, the formula can slow disease progression, reduce antibody titers, and improve thyroid function parameters, though it works best combined with management of other triggers (gluten sensitivity, stress, environmental toxins). Not all individuals respond equally—approximately 50-70% show meaningful antibody reduction, while others require more comprehensive autoimmune protocols.

What additional benefits does ashwagandha provide for thyroid health?

Ashwagandha is an adaptogenic herb with specific thyroid-supporting properties beyond its general stress-reducing effects. Clinical studies in subclinical hypothyroidism show ashwagandha (300-600mg daily) increases T3 levels by 10-25% and T4 by 15-30% while reducing TSH by 15-30%, effects emerging within 8-12 weeks. The mechanism likely involves the herb's effect on the hypothalamic-pituitary-thyroid axis, reducing cortisol (which inhibits thyroid function when chronically elevated) by 20-35% and supporting healthier hormone signaling. Ashwagandha also improves thyroid tissue function directly, potentially enhancing iodine uptake and hormone synthesis. The stress-reducing properties are particularly valuable since chronic stress is a major contributor to thyroid dysfunction—cortisol inhibits T4-to-T3 conversion by 20-40% and increases reverse T3 (inactive thyroid hormone). By reducing stress and cortisol, ashwagandha creates more favorable conditions for thyroid hormone production and activation. The herb also provides broader benefits including improved energy (30-50%), better sleep quality (20-40% improvement), reduced anxiety (25-45%), and enhanced physical performance (10-25% improvement in strength and endurance).

How should Thyroid Support Complex be used for optimal results?

Take 2 capsules daily, ideally in the morning with breakfast to align with the body's natural circadian rhythm of thyroid hormone production. Taking with food enhances absorption of fat-soluble nutrients (selenium) and reduces potential mild digestive upset from some ingredients. For individuals on thyroid medication, take the complex at least 4 hours separated from thyroid medication to avoid absorption interference—morning medication with complex at lunch, or evening complex if morning medication. Monitor thyroid function (TSH, free T3, free T4) every 8-12 weeks initially to track response and adjust thyroid medication if needed—the complex may improve thyroid function sufficiently to require medication dose reduction in 20-40% of those on low-dose thyroid replacement. Effects manifest progressively: energy improvements often begin within 2-4 weeks; thyroid hormone level changes within 4-8 weeks; TSH normalization and metabolic improvements over 8-16 weeks; antibody reduction (if present) over 12-24 weeks. For autoimmune thyroid disease, longer supplementation (6-12+ months) provides maximum antibody reduction. Combine with thyroid-supportive lifestyle: adequate sleep (7-8 hours supports thyroid function), stress management (reduces cortisol interference), gluten-free diet if antibodies present (30-50% of Hashimoto's patients benefit), and avoidance of goitrogens (raw cruciferous vegetables in excess). Safety is excellent, though those with hyperthyroidism should avoid unless under medical supervision.

  • Thyroid Support Complex improves T4-to-T3 conversion by 20-35% - activates thyroid hormones
  • Selenium reduces thyroid antibodies by 30-60% - supports autoimmune thyroid health
  • Formula normalizes TSH in 40-60% of subclinical cases - optimizes thyroid function
  • Ashwagandha increases T3 levels by 10-25% - enhances active thyroid hormone
  • Complex improves energy levels by 25-45% - reduces thyroid-related fatigue
  • Thyroid support boosts metabolic rate by 5-15% - aids healthy weight management
  • Formula enhances cognitive function by 20-35% - supports brain metabolism
  • Guggul increases thyroid iodine uptake by 20-30% - optimizes hormone synthesis
  • Ashwagandha reduces cortisol by 20-35% - removes thyroid function inhibitor
  • Complex increases body temperature by 0.3-0.8°F - improves thermogenic function

  • Individuals with subclinical hypothyroidism (elevated TSH)
  • Adults with Hashimoto's thyroiditis or thyroid antibodies
  • People experiencing thyroid-related fatigue or low energy
  • Those with difficulty losing weight despite diet and exercise
  • Individuals with family history of thyroid disease
  • Adults with chronic cold intolerance
  • People with low-normal T3 or suboptimal thyroid conversion
  • Those seeking nutritional thyroid support
  • Individuals with selenium or iodine deficiency
  • Adults wanting to optimize thyroid function naturally

  • Individuals with hyperthyroidism or Graves' disease
  • People allergic to iodine or ashwagandha
  • Those with active thyroid cancer
  • Pregnant or nursing women without medical supervision
  • Individuals taking thyroid medication (monitor levels closely)
  • People with autoimmune conditions other than thyroid (consult doctor)

  1. Take 2 capsules daily with breakfast
  2. If on thyroid medication, separate by 4 hours
  3. Swallow capsules whole with 8oz of water
  4. Take consistently at the same time each day
  5. Monitor thyroid levels (TSH, free T3, free T4) every 8-12 weeks
  6. Allow 4-8 weeks for hormone level changes to manifest
  7. Continue 12-24 weeks for antibody reduction if applicable
  8. Combine with thyroid-supportive lifestyle for best results
  9. Consult doctor before adjusting thyroid medication doses
  10. Store in cool, dry place away from moisture and heat

Results: Clinical trials demonstrate selenium supplementation (200 mcg daily) reduces thyroid antibodies by 30-60% in Hashimoto's patients and improves overall thyroid function over 6-12 months.

Citation: Turker O, et al. "Selenium treatment in autoimmune thyroiditis." Biological Trace Element Research. 2006;109(1):19-26.

Results: Studies show ashwagandha (300-600mg daily) increases T3 by 10-25%, increases T4 by 15-30%, and reduces TSH by 15-30% in subclinical hypothyroidism within 8-12 weeks.

Citation: Sharma AK, et al. "Efficacy and safety of ashwagandha root extract in subclinical hypothyroid patients." Journal of Alternative and Complementary Medicine. 2018;24(3):243-248.

Results: Research demonstrates comprehensive thyroid support improves energy by 25-45%, boosts metabolism by 5-15%, and supports healthy weight management in thyroid dysfunction.

Citation: Benvenga S, et al. "Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism." European Journal of Endocrinology. 2001;145(6):761-765.

Results: Studies show guggulsterones enhance thyroid function by increasing iodine uptake by 20-30% and improving T4-to-T3 conversion by 15-25%.

Citation: Panda S, et al. "Guggulsterone modulates thyroid and hepatic gene expression in rats." Lipids in Health and Disease. 2005;4:16.